Illumina and MyOme Strike Collaboration Deal Including Strategic Investment to Support MyOme's Clinical Trial That Could Save U.S. Healthcare $200 Billion Annually

SAN DIEGO and MENLO PARK, Calif., Dec. 11, 2025

"MyOme's approach represents an important evolution in the use of genomics for preventive care," said Jakob Wedel, chief strategy and corporate development officer of Illumina. "By combining Illumina's next-generation sequencing technologies with MyOme's AI-integrated risk models, we are helping advance science and generate the clinical evidence needed to transform how diseases are detected and managed."

The collaboration will also support MyOme's ability to expand its commercially available products, including a suite of proactive health and rare disease diagnostic tests. By combining Illumina's leadership in large-scale population health with MyOme's IRMs, MyOme aims to help patients gain access to more accurate, ancestry-relevant risk assessments for many of the leading causes of death. Illumina's technology roadmap will accelerate MyOme's innovation in rare disease testing, further increasing diagnostic yield.

 "This collaboration advances fundamental healthcare science," said Matt Rabinowitz, PhD, Executive Chairman of MyOme. "MyOme is using whole genome sequencing, advanced bioinformatics and AI to deliver lifelong clinical benefits across diverse situations and phenotypes. These include pharmacogenomic insights, analysis of over 150 genes with actionable incidental findings and integrated risk models combining polygenic risk scores, rare variants and other analytes for major cancers, cardiometabolic disease, kidney, liver, cognitive and other diseases. With Illumina's sequencing, we aim to demonstrate how next-generation genomics, integrated with AI-driven risk models, can deliver deeper insights into human biology as well as meaningful economic impact for the U.S.A." 

Strategic Backing from Leading Partners
MyOme's latest financing is further strengthened by continued support from Natera, a global leader in genetic testing and diagnostics that brings deep clinical expertise in cancer detection, women's health, organ health and hereditary disease. Sequoia Capital, The Duquesne Family Office, and others also participated in the financing.

About Illumina
Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as a global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit illumina.com and connect with us on X, Facebook, LinkedIn, Instagram, TikTok, and YouTube.

About MyOme
MyOme is a clinical whole genome analysis platform company helping families understand their risk for inherited diseases. As a leader in genomic plus AI integrated risk modeling, MyOme leverages the power of the whole genome for a lifetime of meaningful and actionable insights. Certified under the Clinical Laboratory Improvement Amendments (CLIA) and certified by the College of American Pathologists (CAP), MyOme is based in Menlo Park, California. For more information, please visit myome.com.

References

1. National Human Genome Research Institute. The Cost of Genome Sequencing and Its Impact on Healthcare. (NIH, 2023).
2. Phillips, K.A., et al. Potential Economic Value of Precision Medicine: Implications for U.S. Healthcare. Health Affairs, 2022.

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SOURCE MyOme, Inc