TCLN, WKN: 868886
Hier einige Informationen
Tuesday February 15 1:48pm
TUSTIN, Calif.--(BUSINESS WIRE)--February 15, Techniclone
Corporation (NASDAQ:TCLN) today announced it has completed an exclusive worldwide licensing transaction with the University of Southern California for its Permeability Enhancing Protein (PEP). The Company also disclosed that US Patent No. 6008319 was issued for this protein and will become part of Techniclone's intellectual property under the terms of the licensing agreement. The terms of the licensing agreement were not disclosed.
The PEP technology is a vital piece of Techniclone's Vasopermeability
Enhancing Technology which is designed to increase the uptake of chemotherapeutic agents into tumors. It is designed to be used in conjunctionwith Techniclone's Vasopermeation Enhancement Agent (VEA) technology platform. Techniclone recently announced the issuance of a key patent in the VEA area. Alan Epstein, M.D., Ph.D, Professor of Pathology at the University of Southern California and the inventor of both the VEA
technology and the discoverer along with colleague Dr. Leslie Kwhali, of the
PEP molecule, stated, "The PEP technology in conjunction with the overall
VEA platform technology completes an already strong package with high potential for application in the field of cancer therapeutics and diagnostics. I am excited about working with the new Techniclone management to bring this technology to commercialization."
The PEP molecule is a segment of a cytokine (cell messenger) called IL-2.
The PEP molecule appears to allow the tumor to become more permeable to
the uptake of drugs while not having toxic side-effects. The PEP patent
covers the use of the molecule in conjunction with targeting molecules such as antibodies to specifically enhance the uptake of drugs in most solid tumors.
Preclinical studies in animal models have shown that drug uptake can be
increased up to 400% in specific instances by using the VEA technology
(including the PEP molecule) as a pretreatment.
Dr. John Bonfiglio, Techniclone's Interim President, stated, "The completion
of the licensing deal and the issuance of the PEP patent are the last key
pieces to the VEA technology platform. Techniclone has now complete
access to this powerful and broad platform technology. This technology fits
very well into the drug development efforts of many pharmaceutical
companies. We look forward to working with Dr. Epstein and his research
group to develop this technology further while we simultaneously advance
discussions on licensing this technology to companies in the cancer
therapeutics area who are interested in delivering more drug to the tumor with potentially fewer side effects."
The New England Research Application Center (Source: Geriann P. Park
and Anna Crull, "Cancer Treatment and Diagnostic Products," report
YC-047N) estimates that $7.6 billion will be spent annually on
chemotherapeutic treatments in the year 2000, reflecting a 9% annual growth
rate - a market Techniclone will target with its proprietary and
patent-protected technology.
All preclinical studies for the VEA technology were conducted at the
University of Southern California (USC), under the leadership of Dr. Alan
Epstein, M.D., Ph.D., the inventor of the VEA technology. Results of the Dr.
Epstein's preclinical studies in the VEA technology have been corroborated
by two physicians at Keio University in Tokyo, Japan. These researchers
achieved similar increases in tumor uptake of anti-cancer agents through
pretreatment with the Vasopermeation Enhancement concept. Findings of this
study, which was conducted independently from Techniclone, were
presented in 1997 at the Annual Society of Nuclear Medicine Meeting.
Company Overview: Techniclone Corporation is a biopharmaceutical
company focused on the development, commercialization and licensing of
unique technologies for the treatment of cancer, primarily based on its
"collateral targeting technologies." These technologies therapeutically target cell structures and cell types, rather than surface cancer cells, as attack solid tumors, without causing damage to surrounding healthy tissue.
The Company has three collateral technologies: Cotara(TM),
The Company also has a direct tumor targeting agent called
Oncolym (R) for the treatment of advanced non-Hodgkin's B-cell
Lymphoma which has been licensed to Schering AG, Germany, which is now
responsible for all existing and future Oncolym(R) clinical trial programs as well as marketing.
Additional information on the Company and its products can be found at
www.techniclone.com.
Safe Harbor Statement: This release may contain certain forward-looking
statements that are made pursuant to the safe harbor provisions of the Private
Securities Litigation Reform Act of 1995. Actual events or results may differ from the Company's expectations as a result of risk factors discussed in Techniclone's reports on file with the U.S. Securities and Exchange
Commission, including, but not limited to, the Company's report on Form
10K for the year ended April 30, 1999 and Form 10Q for the quarter ended
October 31, 1999.
Additional information on the Company and its products can be found at
www.techniclone.com.
Hört sich für mich alles recht interessant an. Hat einer von euch noch andere Informationen (oder gar Meinungen?)
Garion
Hier einige Informationen
Tuesday February 15 1:48pm
TUSTIN, Calif.--(BUSINESS WIRE)--February 15, Techniclone
Corporation (NASDAQ:TCLN) today announced it has completed an exclusive worldwide licensing transaction with the University of Southern California for its Permeability Enhancing Protein (PEP). The Company also disclosed that US Patent No. 6008319 was issued for this protein and will become part of Techniclone's intellectual property under the terms of the licensing agreement. The terms of the licensing agreement were not disclosed.
The PEP technology is a vital piece of Techniclone's Vasopermeability
Enhancing Technology which is designed to increase the uptake of chemotherapeutic agents into tumors. It is designed to be used in conjunctionwith Techniclone's Vasopermeation Enhancement Agent (VEA) technology platform. Techniclone recently announced the issuance of a key patent in the VEA area. Alan Epstein, M.D., Ph.D, Professor of Pathology at the University of Southern California and the inventor of both the VEA
technology and the discoverer along with colleague Dr. Leslie Kwhali, of the
PEP molecule, stated, "The PEP technology in conjunction with the overall
VEA platform technology completes an already strong package with high potential for application in the field of cancer therapeutics and diagnostics. I am excited about working with the new Techniclone management to bring this technology to commercialization."
The PEP molecule is a segment of a cytokine (cell messenger) called IL-2.
The PEP molecule appears to allow the tumor to become more permeable to
the uptake of drugs while not having toxic side-effects. The PEP patent
covers the use of the molecule in conjunction with targeting molecules such as antibodies to specifically enhance the uptake of drugs in most solid tumors.
Preclinical studies in animal models have shown that drug uptake can be
increased up to 400% in specific instances by using the VEA technology
(including the PEP molecule) as a pretreatment.
Dr. John Bonfiglio, Techniclone's Interim President, stated, "The completion
of the licensing deal and the issuance of the PEP patent are the last key
pieces to the VEA technology platform. Techniclone has now complete
access to this powerful and broad platform technology. This technology fits
very well into the drug development efforts of many pharmaceutical
companies. We look forward to working with Dr. Epstein and his research
group to develop this technology further while we simultaneously advance
discussions on licensing this technology to companies in the cancer
therapeutics area who are interested in delivering more drug to the tumor with potentially fewer side effects."
The New England Research Application Center (Source: Geriann P. Park
and Anna Crull, "Cancer Treatment and Diagnostic Products," report
YC-047N) estimates that $7.6 billion will be spent annually on
chemotherapeutic treatments in the year 2000, reflecting a 9% annual growth
rate - a market Techniclone will target with its proprietary and
patent-protected technology.
All preclinical studies for the VEA technology were conducted at the
University of Southern California (USC), under the leadership of Dr. Alan
Epstein, M.D., Ph.D., the inventor of the VEA technology. Results of the Dr.
Epstein's preclinical studies in the VEA technology have been corroborated
by two physicians at Keio University in Tokyo, Japan. These researchers
achieved similar increases in tumor uptake of anti-cancer agents through
pretreatment with the Vasopermeation Enhancement concept. Findings of this
study, which was conducted independently from Techniclone, were
presented in 1997 at the Annual Society of Nuclear Medicine Meeting.
Company Overview: Techniclone Corporation is a biopharmaceutical
company focused on the development, commercialization and licensing of
unique technologies for the treatment of cancer, primarily based on its
"collateral targeting technologies." These technologies therapeutically target cell structures and cell types, rather than surface cancer cells, as attack solid tumors, without causing damage to surrounding healthy tissue.
The Company has three collateral technologies: Cotara(TM),
The Company also has a direct tumor targeting agent called
Oncolym (R) for the treatment of advanced non-Hodgkin's B-cell
Lymphoma which has been licensed to Schering AG, Germany, which is now
responsible for all existing and future Oncolym(R) clinical trial programs as well as marketing.
Additional information on the Company and its products can be found at
www.techniclone.com.
Safe Harbor Statement: This release may contain certain forward-looking
statements that are made pursuant to the safe harbor provisions of the Private
Securities Litigation Reform Act of 1995. Actual events or results may differ from the Company's expectations as a result of risk factors discussed in Techniclone's reports on file with the U.S. Securities and Exchange
Commission, including, but not limited to, the Company's report on Form
10K for the year ended April 30, 1999 and Form 10Q for the quarter ended
October 31, 1999.
Additional information on the Company and its products can be found at
www.techniclone.com.
Hört sich für mich alles recht interessant an. Hat einer von euch noch andere Informationen (oder gar Meinungen?)
Garion