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QUVIVIQ™ (daridorexant) sales reached CHF 142 million in the first nine months of 2026, with growth accelerating quarter-on-quarter. Idorsia reaffirms its full-year 2026 guidance and remains focused on further accelerating growth, maximizing the commercial opportunity of QUVIVIQ, and preparing the launch of TRYVIO/JERAYGO under the new leadership of CEO Roland Wandeler.
Allschwil, Switzerland – October 29, 2026
Idorsia Ltd (SIX: IDIA) is a commercial-stage biopharmaceutical company with two products, each with blockbuster potential, and a differentiated portfolio of first- or best-in-class therapies. The company today announced its financial results for the first nine months of 2026.
Roland Wandeler, CEO of Idorsia, commented:
“My first month at Idorsia has reinforced my belief that we have the assets, strategy and people to create substantial value. We have two products with blockbuster potential, a focused strategy, and a team fully committed to execution. Accelerating QUVIVIQ growth is our number one priority, and I see multiple opportunities to expand its reach and impact. Our recent pediatric insomnia findings, including the opportunity in children with autism spectrum disorder, reinforce my belief that we are only beginning to unlock the full potential of daridorexant. At the same time, we have identified a focused and capital-efficient pathway to realize the significant potential of TRYVIO/JERAYGO. With two products that each have blockbuster potential, we are entering a period where disciplined execution can translate innovation into substantial value for patients and shareholders.”
Maximize the current QUVIVIQ® opportunity in insomnia
QUVIVIQ continues to benefit from five reinforcing growth drivers: accelerating demand, expanding geographic reach, broader patient access, increasing penetration into primary care, and multiple lifecycle expansion opportunities. Together, these drivers contributed to net sales growth of 54% to CHF 142 million in the first nine months of 2026 (9M 2025: CHF 92 million) across North America and Europe.
Key developments during the third quarter included:
Together, these developments reinforce our conviction that we are only beginning to unlock the full commercial and clinical potential of daridorexant.
Unlock the value of TRYVIO™ / JERAYGO™ (aprocitentan)
TRYVIO/JERAYGO continues to demonstrate the characteristics of a significant commercial opportunity, supported by growing physician awareness of the unmet need in difficult-to-control and resistant hypertension, a differentiated efficacy and tolerability profile, and emerging real-world experience. During the quarter, new data presented at AHA Hypertension 2026 and ASN Kidney Week further reinforced the product's potential across high-risk patient populations (press release). In parallel, Idorsia and SPV investors announced a proposed commercialization partnership to unlock the blockbuster potential of TRYVIO/JERAYGO through a focused specialist-led launch strategy. The proposed combination of dedicated launch capital and participation in future product revenues would create a focused and capital-efficient pathway to realize the product's commercial potential. This approach also enables shareholders to participate more directly in the value created by the asset (press release).
Expand the long-term value of daridorexant
In a Phase 2 pediatric insomnia study, daridorexant not only improved sleep but also showed unexpected improvements in affect and behavior, cognition, and daily functioning in children with ASD or ASD-like characteristics. Supported by these findings, internal research, and external scientific evidence, Idorsia plans to initiate a dedicated development program in ASD, opening up a new scientific avenue for daridorexant (press release). Further details will be presented in H1 2027 following regulatory discussions.
Advance innovation and the pipeline
While commercial execution remains the company's primary focus, Idorsia continued to advance a selective portfolio of future growth opportunities during the quarter. Highlights included the initiation of the pivotal Phase 3 FAB-KLEAR study of lucerastat in Fabry disease, as well as the signing of a co-development and commercialization agreement with Nxera Pharma covering Japan and selected Asia-Pacific markets (press release). The company also continued progress across first-in-class immunology and neuroscience programs while demonstrating disciplined capital allocation by discontinuing the CCR6 program after the results did not live up to expectations and reallocating resources toward higher-priority opportunities.
Arno Groenewoud, Chief Financial Officer of Idorsia, commented:
“Our financial performance in the first nine months of 2026 was in line with our expectations, reflecting continued growth of QUVIVIQ and disciplined management of our operating expenses. Based on our year-to-date performance and outlook for the remainder of the year, we confirm our full-year 2026 guidance with an improvement of the US GAAP operating loss. We remain in a strong liquidity position, with QUVIVIQ’s commercial business profitable, enabling us to invest today in the growth of tomorrow.”
Financial highlights for 9M 2026
Financial Guidance
The financial guidance for 2026 reflects continued growth of QUVIVIQ, investment in the lucerastat registration program, and development of the company’s immunology portfolio. TRYVIO/JERAYGO revenues and investments are not included, as these will be considered in any potential partnership agreement. All amounts exclude unforeseen events and any potential upsides from new direct-to-patient distribution models currently being implemented in several geographies and revenue related to additional business development activities.
Financial results nine months 2026
Net revenue of CHF 172 million in the first nine months of 2026 resulted from product sales (CHF 142 million), product sales to partners (CHF 12 million), and contract revenues (CHF 18 million). This compares to net revenue of CHF 173 million in the first nine months of 2025 as a result of QUVIVIQ product sales (CHF 92 million), product sales to partners (CHF 3 million), and contract revenue (CHF 78 million).
US GAAP operating expenses were CHF 272 million in the first nine months of 2026, with an increase of CHF 20 million compared to the first nine months of 2025 (excluding a one-off gain of CHF 90 million in the first nine months of 2025). Cost of sales of CHF 33 million increased by CHF 21 million due to higher product sales. R&D expenses of CHF 80 million and SG&A expenses of CHF 159 million together remain almost flat.
US GAAP net loss in the first nine months of 2026 of CHF 206 million compared to CHF 34 million in the first nine months of 2025. The increased net loss was primarily driven by the increase of financial expenses of CHF 54 million (mainly non-cash interests on the debt notes, non-cash accretion of the New Money Facility loan, and non-cash debt extinguishment loss), as well as the increase in operating expenses of CHF 110 million, of which CHF 21 million related to cost of sales driven by higher product sales and CHF 90 million relate to a non-recurring one-off gain in 2025.
The US GAAP net loss resulted in a net loss per share of CHF (0.80) (basic and diluted) in the first nine months of 2026, compared to a net loss per share of CHF (0.17) basic and diluted in the first nine months of 2025.
* Idorsia measures, reports, and issues guidance on non-GAAP operating performance. Idorsia believes that these non-GAAP financial measurements more accurately reflect the underlying business performance and therefore provide useful supplementary information to investors. These non-GAAP measures are reported in addition to, not as a substitute for, US GAAP financial performance.
Non-GAAP net loss in the first nine months of 2026 amounted to CHF 123 million; the difference versus US GAAP net loss was mainly driven by depreciation and amortization (CHF 11 million), share-based compensation (CHF 9 million), accretion expenses (CHF 16 million), interest expense recognized under the R-Bridge royalty monetization agreement (CHF 6 million) and debt extinguishment loss (CHF 47 million) relating to the repayment of the New Money Facility loan, offset by non-cash revenue recognized under the R-Bridge royalty monetization agreement (CHF 7 million).
The non-GAAP net loss resulted in a net loss per share of CHF 0.48 (basic and diluted) in the first nine months of 2026, compared to a net loss per share of CHF 0.32 (basic and diluted) in the first nine months of 2025.
About the Pharmakon Secured Term Loan
In June 2026, Idorsia entered into a senior secured term loan agreement of up to CHF 250 million with investment funds managed by Pharmakon Advisors, LP, at a fixed 7% interest rate (“Secured Term Loan”). Idorsia received a first tranche of CHF 150 million and partially used it to fully repay the CHF 105 million drawn under the previously existing New Money Facility, plus OID and interests. The transaction removed near-term maturities and strengthened Idorsia’s liquidity profile. Additional tranches may be drawn – subject to customary conditions – providing further financial flexibility to support targeted initiatives to accelerate growth and long‑term value creation.
Liquidity and indebtedness
Liquidity on September 30, 2026, amounted to CHF 85 million. This amount does not include the remaining CHF 100 million available under the secured term loan.
* rounding differences may occur
** The debt notes issued by Idorsia Investments SARL (“SPV”) in exchange for convertible bonds are senior secured with the shares in Idorsia Investments SARL. The A Notes only benefit from a limited and subordinated Swiss-law governed guarantee by Idorsia Ltd.
Results Day Center
Investor community: To make your job easier, we provide all relevant documentation, including the financial report, via the Results Day Center on our corporate website: www.idorsia.com/results-day-center.
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Notes to the editor
About Idorsia
The purpose of Idorsia is to discover, develop and commercialize innovative medicines to help more patients. To achieve this, we will develop Idorsia into a leading biopharmaceutical company, with a strong scientific core.
Headquartered near Basel, Switzerland – a European biotech hub – Idorsia has a highly experienced team of dedicated professionals, covering all disciplines from bench to bedside; QUVIVIQ™ (daridorexant), a different kind of insomnia treatment with the potential to revolutionize this mounting public health concern; strong partners to maximize the value of our portfolio; a promising in-house development pipeline; and a specialized drug discovery engine focused on small-molecule drugs that can change the treatment paradigm for many patients. Idorsia is listed on the SIX Swiss Exchange (ticker symbol: IDIA).
For further information, please contact
Kevin Boss
Director, Investor Relations
Idorsia Pharmaceuticals Ltd, Hegenheimermattweg 91, CH-4123 Allschwil
+41 58 844 10 10
investor.relations@idorsia.com – media.relations@idorsia.com – www.idorsia.com
The above information contains certain "forward-looking statements", relating to the company's business, which can be identified by the use of forward-looking terminology such as “intend”, "estimates", "believes", "expects", "may", "are expected to", "will", "will continue", "should", "would be", "seeks", "pending" or "anticipates" or similar expressions, or by discussions of strategy, plans or intentions. Such statements include descriptions of the company's investment and research and development programs, business development activities and anticipated expenditures in connection therewith, descriptions of new products expected to be introduced by the company and anticipated customer demand for such products and products in the company's existing portfolio. Such statements reflect the current views of the company with respect to future events and are subject to certain risks, uncertainties and assumptions. Many factors could cause the actual results, performance or achievements of the company to be materially different from any future results, performances or achievements that may be expressed or implied by such forward-looking statements. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described herein as anticipated, believed, estimated or expected. Idorsia has transferred its rights for aprocitentan, cenerimod and selatogrel to Idorsia Investments SARL to allow the repayment of notes issued in connection with the repurchase offer completed in August 2025. More details on the transfer can be found in the financial report of Idorsia Investments SARL.
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