Name Date shares traded shares held Price type (sell/buy) option
BRENNER LOUIS MD 11/14/2021 40,328.00 288,576.00 0.81 Sell No
BRENNER LOUIS MD 11/14/2021 125,582.00 328,904.00 n/a Buy No
BRENNER LOUIS MD 05/09/2021 25,215.00 203,322.00 1.11 Sell No
BRENNER LOUIS MD 05/09/2021 83,721.00 228,537.00 n/a Buy No
WHOLIHAN EDWARD 12/16/2020 68,550.00 121,272.00 1.36 Sell No
BRENNER LOUIS MD 12/16/2020 103,116.00 144,816.00 1.36 Sell No
WHOLIHAN EDWARD 12/16/2020 164,822.00 189,822.00 n/a Buy No
BRENNER LOUIS MD 12/16/2020 247,932.00 247,932.00 n/a Buy No
WHOLIHAN EDWARD 05/08/2018 25,000.00 25,000.00 1.59 Buy No
HBM BioCapital II LP 11/05/2017 71,428.00 1,638,330.00 14.00 Buy No
HBM BioCapital II LP 11/05/2017 140,841.00 1,566,902.00 n/a Buy No
HBM BioCapital II LP 11/05/2017 1,426,061.00 1,426,061.00 n/a Buy No
FHM VI, L.L.C. 11/05/2017 500,000.00 3,330,373.00 14.00 Buy No
FHM VI, L.L.C. 11/05/2017 2,830,373.00 2,830,373.00 n/a Buy No
Hadley Harbor Master Investors (Cayman) L.P. 11/05/2017 757,684.00 757,684.00 n/a Buy No
Third Rock Ventures III, L.P. 11/05/2017 215,000.00 2,790,964.00 14.00 Buy No
Third Rock Ventures III, L.P. 11/05/2017 2,575,964.00 2,575,964.00 n/a Buy No
Kraus Stephen 11/05/2017 0.00 n/a n/a Buy No
Kraus Stephen 11/05/2017 0.00 n/a n/a Buy No
TEPPER ROBERT I 11/05/2017 215,000.00 2,790,964.00 14.00 Buy No
TEPPER ROBERT I 11/05/2017 2,575,964.00 2,575,964.00 n/a Buy No
Bessemer Venture Partners VII L.P. 11/05/2017 36,000.00 2,263,365.00 14.00 Buy No
Bessemer Venture Partners VII L.P. 11/05/2017 2,227,365.00 2,227,365.00 n/a Buy No
Topper James N 11/05/2017 500,000.00 3,330,373.00 14.00 Buy No
Topper James N 11/05/2017 254,409.00 2,830,373.00 n/a Buy No
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