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Amarillo Bioscience - ein aussichtsreicher Wert!


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2teSpitze:

Amarillo Bioscience - ein aussichtsreicher Wert!

2
04.04.08 18:53
Bin schon länger investiert. Glaube an die Story und an größere Gewinne in der Zukunft.

Hab hier keinen Thread gefunden. Ist sonst noch jemand dabei?
*Spitzle2*
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Werbung

Entdecke die beliebtesten ETFs von SPDR


2teSpitze:

War heute bei

2
04.04.08 18:57
wo:

Amarillo Biosciences, Inc. – Biotech vom Feinsten aus den USA

Die Yalta AG freut sich Ihnen heute die Aktie von Amarillo Biosciences aus den USA vorstellen zu dürfen.

Unsere Empfehlung: „Buy“

„Amarillo Biosciences (AMAR) ist Biotech vom Feinsten. Gegründet bereits im Jahre 1984, war und ist die Entwicklung oraler Anwendungsformen von Interferon (Interferon Alpha – IFNΩ) zur Behandlung verschiedener Krankheiten bei Menschen und Tieren das vorrangige Unternehmensziel.“

Unser Fazit:

„Die Aktie steht momentan bei 0,198 EUR – Market Cap liegt bei ca. 6 Mio. EUR – und ist unserer Meinung nach stark unterbewertet. (RESEARCH DOWNLOAD) Aus unserer Sicht ist AMAR einer der verheißungsvollsten Werte überhaupt. Enorme Marktpotentiale und mehrfache Vervielfachungen sind Möglich – da die ersten Zulassungen in den nächsten 12 Monaten zu erwarten sind.“

Quelle: wallstreet-online
*Spitzle2*
Antworten
2teSpitze:

Etwas älter!

 
04.04.08 19:08
Amarillo Biosciences "trading-buy"

28.02.2008
Trendstock Research

München (aktiencheck.de AG) - Die Experten von "Trendstock Research" vergeben für die Amarillo Biosciences-Aktie (ISIN US02301P1066 / WKN 917640) das Rating "trading-buy".

Als innovatives Biotechnologie-Unternehmen arbeite Amarillo an mehreren aussichtsreichen Medikamenten mit einem Milliardenpotenzial. Das erste Präparat könnte im Jahr 2011 an den Markt gebracht werden. Unter fundamentalen Gesichtspunkten erscheine der Zeitpunkt für einen Einstieg in die Aktie daher recht früh. Allerdings dürfte Amarillo im laufenden Jahr mehrere Phase-II-Studien abschließen, was im Erfolgsfall eine signifikante Höherbewertung des Unternehmens bewirken könnte. Aktuell liege die Marktkapitalisierung bei lediglich 5,9 Mio. Euro. Vor diesem Hintergrund sehe man eine interessante Trading-Chance. Anleger sollten sich rechtzeitig positionieren und bei guten Nachrichten dann auch mal Gewinne mitnehmen.

Die Experten von "Trendstock Research" vergeben für die Amarillo Biosciences-Aktie das Rating "trading-buy". Zur Absicherung sollte ein Stopp-Kurs bei 0,160 Euro gesetzt werden. (Analyse vom 28.02.2008)

Quelle: Trendstock Research
*Spitzle2*
Antworten
Gelöschter Beitrag. Einblenden »
#4

2teSpitze:

Auch hier tut sich was!

 
30.07.09 11:09
"An der Börse verdient man nur Schmerzensgeld. Erst kommen die Schmerzen, dann das Geld." (A. Kostolany)
Antworten
zettma:

Tja

 
15.12.09 15:56
mal sehn was hier in den nächsten Tagen passiert.
Antworten
zettma:

Kann

 
23.12.09 11:42
es kaum abwarten bis Januar! Dann kommen endlich die endgültigen Ergebnisse!
Antworten
estel2005:

Zettma

 
28.12.09 16:56
Was für Ergebnisse kommen denn im Januar?

Danke im Voraus.
Antworten
zettma:

.

2
28.12.09 20:55
Amarillo Biosciences Issues Update on Australian Phase 2 Clinical Trial Testing orale Interferon als Vorbeugung gegen Grippe

Amarillo, TX - (Marketwire - 17. Dezember 2009) - Amarillo Biosciences, Inc. (ABI) (OTCBB: AMAR) Gab heute bekannt, dass seine laufenden Studie von oral verabreichtem Interferon als Prävention / Behandlung der Influenza und andere Atemwegserkrankungen in Perth, Australien kurz vor dem Abschluss. Es wurden insgesamt 200 gesunden Probanden wurden in dieser klinischen Phase-2-Studie um das orale Interferon oder Placebo nehmen Lutschtabletten einmal täglich für 16 Wochen, gefolgt von 4 Wochen nach der Behandlung Beobachtung. Die Behandlung der Studie wurde im November mit über 80% der Freiwilligen Abschluss 16 Wochen der Studie Medikamente abgeschlossen. Alle Themen werden der 4 Wochen nach der Behandlung Beobachtung durch die Ende des Jahres abzuschließen.

Das Ziel dieser Studie ist es festzustellen, ob die Freiwilligen, die orale Interferon Erfahrung nehmen weniger Atemwegserkrankungen und / oder weniger schwere Symptome während der Winter kalt / Grippe-Saison in Australien. Um dieses Ziel zu erreichen, wurde die Studie in einer Placebo-kontrollierten durchgeführt, double-blind Weise. Die Hälfte der Freiwilligen erhielten Pastillen, die die Gesellschaft Interferon-Alpha-Produkt, während die andere Hälfte erhielt ein Placebo (Placebo). Während der Behandlung weder die Forscher noch die Probanden wussten, welche Themen Interferon erhalten und die Placebo erhielten.

Erst wenn alle betroffenen Personen haben die Nachbehandlung Beobachtung Phase abgeschlossen und alle Daten Studie wurde in einem verschlossenen elektronische Datenbank eingegeben wird der Code gebrochen werden, um die Behandlung zu jedem Thema zugeordnet offenbaren. Fertigstellung des Daten-und Brechen der Behandlung Code wird im Januar statt, gefolgt von ausführlichen statistischen Analyse. Die Ergebnisse der Studie werden so bald wie eine vollständige Analyse aller Daten Studie angekündigt, wurde abgeschlossen.

Die Studie wird von Professor Manfred Beilharz und seine Mitarbeiter in der Mikrobiologie und Immunologie Disziplin (BBCS) an der University of Western Australia mit primären Mittel aus dem Department of Health, Government of Western Australia.

Über Amarillo Biosciences

Amarillo Biosciences, Inc. ist ein US-Biotechnologie-Firma, die in globale Partnerschaft mit der Hayashibara-Fraktion, die ebenfalls im Besitz 7% der Aktien Amarillo Biosciences und hat über 18 Millionen Dollar in Form von Darlehen, Zuschüsse und Beteiligungen zur Verfügung gestellt. Der Schwerpunkt der Firma ist sehr umfangreich und laufenden F & E im Bereich der Verwendung von niedrig dosiertem, oral verabreichtem Interferon zur Behandlung einer Vielzahl von Bedingungen, einschließlich Influenza, Hepatitis C, chronischer Husten und opportunistischen Infektionen bei Patienten, die HIV-positiv sind. In seiner 25-jährigen Geschichte des Unternehmens hat fast 40 Millionen Dollar investiert, um das orale Interferon als therapeutisches Mittel zu schaffen. Die meisten dieser Mittel wurden in klinischen Studien in dem Bestreben, die FDA-Zulassung für Interferon zu erreichen investiert. Weitere Informationen finden Sie auf der Webseite abrufbar unter http://www.amarbio.com/.

Mit Ausnahme der hierin enthaltenen historischen Informationen, die in dieser Pressemitteilung behandelten Themen sind vorausschauende Aussagen, die Risiken und Unsicherheiten, einschließlich der Unsicherheiten Hinblick auf die Produktentwicklung, Unwägbarkeiten hinsichtlich der erforderlichen behördlichen und sonstigen staatlichen Genehmigungen, die Abhängigkeit von der firmeneigenen Technologie beinhalten, Unsicherheit der Marktakzeptanz von oral verabreichtem Interferon oder des Unternehmens anderen Produktkandidaten und andere Risiken, die von Zeit zu Zeit in den Einreichungen des Unternehmens bei der Securities and Exchange Commission. Insbesondere finden Sie unter "Item 1. Beschreibung des Business" und "Item 7A. Qualitative und quantitative Angaben über Market Risk" von des Unternehmens auf Formblatt 10-K für das Geschäftsjahr zum 31. Dezember 2008.

Antworten
2teSpitze:

Dann sind wir doch mal

 
29.12.09 19:06
gespannt, was das neue Jahr uns bringt.
"An der Börse verdient man nur Schmerzensgeld. Erst kommen die Schmerzen, dann das Geld." (A. Kostolany)
Antworten
zettma:

Es wird Zeit

 
06.01.10 20:41
das News kommen. (Warten)
Antworten
2teSpitze:

Oder steigende Kurse!

 
09.01.10 10:54
"An der Börse verdient man nur Schmerzensgeld. Erst kommen die Schmerzen, dann das Geld." (A. Kostolany)
Antworten
macos:

vom 1. Januar 2010

13
13.01.10 12:04
netter Artikel über Veldona

www.dailymail.co.uk/health/article-1239932/...ld-flu-bugs.html

Gruss macos
Antworten
macos:

hier dürfte bei guten Ergebnissen

15
13.01.10 12:18
der Studie, bald ein Push kommen?

noch mal auf Türkisch*g*
www.hurriyetport.com/news/135/ARTICLE/16781/2010-01-02.html
Antworten
macos:

und noch einer

15
13.01.10 12:23
Cure for cold and flu: a lozenge, say scientists

ibnlive.in.com/news/...y-scientists/108132-17.html?from=search
Antworten
zettma:

Wir

 
20.01.10 13:46

warten immer noch auf News. Hätten doch schon letzte Woche kommen sollen.

 

Hmmm

Antworten
macos:

wann kommen die Studienergebnisse?

10
01.02.10 22:34
ein Partner von Amarillo meldet sich zu Wort.

Ahmedabad-based Intas Pharmaceuticals (Intas) has entered into a strategic partnership with US biotechnology company, Amarillo Biosciences, Inc (ABI), whereby Intas will sponsor clinical trials of ABI’s orally administered interferon-alpha lozenges for influenza, which could also be used in combating the H1N1 virus.

When asked about the prospects of Intas Pharmaceuticals-Amarillo Biosciences partnership, Dr Samir Sangitrao, assistant general manager - regulatory affairs, Intas Biopharmaceuticals,says, “Intas has submitted the required documents to DCGI for approval of its clinical trial in India. We are expecting the approval very soon. After getting the approval, Intas is planning to conduct a therapeutic clinical trial covering 500 patients with Amarillo Biosciences’ patented orally administered interferon-alfa lozenges. Amarillo has already completed animal studies including toxicity studies as well as several other clinical trials in the US and rest of the world.”

“Intas is developing a natural interferon-based therapeutic solution for influenza in general (which will also cover swine flu). Oral interferon will be used to prevent influenza, and, as a treatment, it will also be used to reduce the severity of symptoms. The flu virus does not mutate to evade the effects of interferon. Oral interferon will have no interactions with influenza vaccines,” he adds.

He further says that the ongoing flu clinical trial in Australia, which is preventive in nature, is well-timed to help Intas deal with the next wave of swine flu or any other viral respiratory infections efficiently. Report of this preventive study is expected in a few months from now. This will further enhance the usability of orally administered interferon-alfa lozenges for preventing influenza and decrease the morbidity caused due to influenza.
biospectrumindia.ciol.com/content/BioSpecial/11001132.asp
Antworten
zettma:

Tja

3
02.02.10 13:01
die hätten eigentlich schon da sein sollen. Komisch.
Antworten
macos:

News

7
03.02.10 17:47
Amarillo Biosciences Announces Preliminary Results That Indicate Influenza-Like Illness Incidence Reduced From 71% to 43% in Vaccinated Patients Treated With Oral Interferon, Symptoms Also Lessened
Analysis of Australian Phase 2 Oral Interferon Clinical Trial Continuing
finance.yahoo.com/news/...ences-iw-862172975.html?x=0&.v=1
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Kleine_prinz:

News ;-)))

 
16.02.10 18:47

Amarillo Biosciences Announces Australian Phase 2 Oral Interferon Clinical Trial Indicates Benefit in Preventing Influenza-Like Illness in Older Participants

February 16, 2010: 12:30 PM ET

Amarillo Biosciences, Inc. (ABI) (OTCBB: AMAR) today announced additional preliminary results from the recently completed Phase 2 clinical trial conducted in Perth, Australia at the University of Western Australia with Professors David Smith and Manfred Beilharz as principal investigators.

The Company previously reported results of a post-hoc analysis, which found that subjects given interferon who had received seasonal influenza vaccine prior to enrollment had a significantly lower incidence of influenza-like illness during the study, compared to subjects in the placebo group who had been vaccinated. Further exploratory analyses have discovered that the incidence of influenza-like illness, the primary study endpoint, was significantly reduced from 60% to 24% in subjects 55 years of age or older who received interferon, compared to subjects in the placebo group who were at least 55 years old at the start of the study.

Similar to what has been observed in studies of other human diseases, preliminary analysis indicates that low-dose oral interferon therapy was safe in this study. No significant differences were found between the groups in the number or severity of adverse events reported. Placebo subjects reported an average of 1.4 adverse events, compared to an average of 1.3 adverse events reported per interferon-treated subject.

A total of 200 healthy human volunteers were enrolled in this study to take a once daily dose of oral interferon or placebo for 16 weeks as prevention of influenza-like illness during the 2009 Australian cold and flu season. The H1N1 (2009) influenza virus was the major circulating virus in Perth during the duration of the trial and was estimated to account for at least 90% of influenza viruses, according to the Australian Department of Health of Western Australia. Blood samples were collected at the beginning and the end of the study for serological analysis. Once available, these serology data will help identify those subjects who had an increase in antibodies to particular cold and flu viruses, including the H1N1 (2009) influenza virus.

Separately, ABI announced that Oromucosal Administration of Interferon to Humans, a review article authored by Manfred W. Beilharz and others, was published in Pharmaceuticals. The article may be viewed at: http://www.mdpi.com/1424-8247/3/2/323.

About Amarillo Biosciences

Amarillo Biosciences, Inc. is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 5.9% of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R&D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including influenza, hepatitis C, chronic cough, and opportunistic infections in patients who are HIV positive. In its 25-year history, the Company has invested nearly $40 million to establish oral interferon as a therapeutic agent. The majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the web site at http://www.amarbio.com/.

Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" and "Item 7A. Qualitative and Quantitative Disclosures About Market Risk" of the Company's Form 10-K for the fiscal year ended December 31, 2008.

Investor Relations: Philippe Niemetz PAN Consultants, Ltd. e-mail: p.niemetz@panconsultants.com Tel: 800-477-7570; 212-344-6464 Fax: 212-618-1276 Joseph M. Cummins, DVM, PhD Amarillo Biosciences, Inc. e-mail: jcummins@amarbio.com Tel: 806-376-1741 x 13 Fax: 806-376-9301 http://money.cnn.com/news/newsfeeds/articles/marketwire/0587541.htm
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Kleine_prinz:

Gute News ;-)))))))))))))

 
05.03.10 12:22

http://finance.yahoo.com/news/...s-and-iw-428381766.html?x=0&.v=1

 

Übersetzung durch google fish ;-)))

Amarillo-Biowissenschaften und Intas pharmazeutische Produkte unterzeichnen Lizenz und Versorgungsabkommen, Mundinterferon zu benutzen, um Grippe in Indien und in Nepal zu behandeln

Intas pharmazeutisch klinische Studie der Phasen-3 in Indien starten, um der Amarillo-Biowissenschaften gegen Grippe zu prüfen Mundinterferon

Pressekommuniqué-Quelle: Amarillo Biosciences, Inc. am Donnerstag, dem 4. März 2010, 11:31 morgens EST

AMARILLO, TX--(Marketwire - 03/04/10) - Amarillo Biosciences, Inc. (ABI) (OTC.BB: AMAR - Nachrichten) heute verkündet, dass sie eine Lizenz und ein Versorgungsabkommen mit den begrenzten Intas pharmazeutischen Produkten durchgeführt hat (Intas), eins der Spitzen20 pharmazeutischen Unternehmen in Indien. Intas Pläne, zum einer double-blind, Placebo-kontrollierten klinischen Studie der Phase 3 ABI der mündlich ausgeübten Interferonalpha Rauten in Indien Ende Märzes zu starten. Die Studie umfaßt bis 520 Patienten mit klinischen Zeichen und Symptomen der Grippe. Intas zahlt ABI eine Abgabe auf Nettoumsätzen in Indien und in Nepal, nachdem vermarktende Zustimmung erreicht ist.

Das Virus H1N1 fährt fort, in Indien zu verteilen. Die Zielsetzung der klinischen Studie, die in Indien geplant wird, ist, die Sicherheit und die Wirksamkeit von Mundinterferon der niedrigen Dosis festzustellen, wenn sie die Schwierigkeit der Infektion mit Grippeviren wie H1N1 verringert. Eine klinische Studie der Phase 2, die vor kurzem in Perth abgeschlossen wurde, Australien zeigte, dass Rauten Interferonalpha ABIS sicher und vorteilhaft waren, als gegeben als Verhinderung gegen Atmungsviren, einschließlich Grippe.

In der double-blind Studie, die in Perth geleitet wurde, wurden 200 gesunden Freiwilligern Rauten oder Placebo Interferonalpha Niedrigdosis ABIS einmal täglich für 16 Wochen während der Winterkälte- und -grippejahreszeit in West australien gegeben. Einleitende Analyse hat gezeigt, dass Interferonalpha Rauten von den schädlichen Wirkungen frei waren und zu eine Verschiebung in der Symptomschwierigkeit von gemäßigtem zu mildem geführt. Wichtig verringerte prophylactiker Gebrauch von Niedrigdosis Interferonalpha Rauten erheblich die Rate Grippe-wie der Krankheit im Studienfreiwilligeralter 55 Jahre und älter, die im Allgemeinen betrachtet werden, am hohen Risiko für Grippe zu sein. Die Firma plant, volle Studienresultate freizugeben, wenn Serologieprüfung abgeschlossen wird.

„Grippeviren ändern sich, um den Effekten der Antivirendrogen auszuweichen. Grippeviren ändern sich nicht, um Interferon auszuweichen, aber anstatt haben sie eine Strategie, zum des Wirtsinterferonsystems zu sabotieren. Indem wir mündlich Leuteinterferon geben, glauben wir, dass wir diese Virenstrategie überwinden können. Es ist mein Glaube, dass Niedrigdosis Mundinterferon eine vorteilhafte Therapie aller Grippeviren ist, nicht gerade die Belastung H1N1,“ sagte Dr. Joseph M. Cummins, Präsident und Vorstandsvorsitzende von ABI.

Über Amarillo-Biowissenschaften
Amarillo Biosciences, Inc. ist ein US-Biotechnologieunternehmenbetrieb in der globalen Teilhaberschaft mit der Hayashibara Gruppe, die auch 6% von Amarillo-Biowissenschaftanteilen hält und über $18 Million in den Darlehen, in den Bewilligungen und in den Billigkeits-Investitionen zur Verfügung gestellt hat. Der Primärfokus der Firma ist umfangreicher und laufender R&D in den Gebrauch von Niedrigdosis, mündlich ausgeübtes Interferon als Behandlung für eine Vielzahl von Bedingungen, einschließlich Grippe, Hepatitis C, chronischen Husten und opportunistische Infektion bei Patienten, die HIV-POSITIV sind. Die Firma hat fast $40 Million investiert, um Mundinterferon als therapeutisches Mittel herzustellen. Die Majorität jener Kapital wurden in den klinischen Studien in einer Bemühung, FDA-Zustimmung für Interferon zu erzielen investiert. Zusätzliche Information ist auf dem Netz bei http://www.amarbio.com/ vorhanden.

Über Intas pharmazeutische Produkte
Intas pharmazeutisch Produkte Ltd. ist ein Indien gegründetes pharmazeutisches Unternehmen mit drei Dekaden der Erfahrung in der Gesundheitspflegeindustrie und der globalen Anwesenheit in 42 Ländern weltweit. Die Firma hat einen starken Fokus in den Bereichen der CNS-Störungen, der kardiovaskulären Krankheit, des Diabetes, des Darmleidens, der Urologie, des Schmerzmanagements, der Tiergesundheitspflege, der Onkologie und der Biotechnologie. Im Binnenmarkt ist die Firma unter den Spitzen20 Produktfirmen steuerpflichtig. Die Firma hat eine starke Anwesenheit das europäische, das BRITISCH, in US und in den lateinamerikanischen pharmazeutischen Märkten. Die Firma lässt Entwicklungsproduktionsanlagen laufen und hat Sachkenntnis mit einer Strecke der Formulierungen von Tabletten zu injectables. Die Firma hat eine umgebenformulierungentwicklung des völlig integrierten Modells, API und Formulierungherstellung und Marketing. Gesamtverkäufe für 2008-2009 betrugen 11.6 Milliarde Rupien (US$240 Million). Zusätzliche Information ist auf dem Netz an vorhanden: http://www.intaspharma.com/.

Außer den historischen Informationen, die hierin enthalten werden, sind die Sachen, die in dieser Pressenotiz beraten über werden, vorausschauende Aussagen, die Risiken und Ungewissheiten, einschließlich die Ungewissheiten miteinbeziehen, die auf Produktentwicklung, die Ungewissheiten bezogen werden, die auf der Notwendigkeit an regelndem bezogen werden und andere Regierungszustimmungen, Abhängigkeit auf eigener Technologie, Ungewissheit der Marktannahme anderen von des Munddes interferon oder von anderer Anwärter des Produktes der Firma und riskiert gelegentlich einzeln aufgeführt in den Archivierungen der Firma mit der Börsenaufsichtsbehörde. Insbesondere sehen Sie „Beschreibung des Einzelteil-1. des Geschäfts“ und „des Einzelteils 7A. Qualitative und quantitative Freigabe über Konjunkturrisiko“ der Form 10-K der Firma für das Finanzjahr beendete 31. Dezember 2008.

Kontakt:



Beziehungen zwischen den Investoren:
Philippe Niemetz
WANNE Berater, Ltd.
eMail: p.niemetz@panconsultants.com
Telefon: 800-477-7570
212-344-6464
Telefax: 212-618-1276
Joseph M. Cummins, DVM, PhD
Amarillo Biosciences, Inc.
eMail: jcummins@amarbio.com
Telefon: 806-376-1741 x 13
Telefax: 806-376-9301
Antworten
Kleine_prinz:

Ganz wichtig.... ;-)

 
05.03.10 12:35

Wenn das Gelingt dann wird hier Bald die hölle Loss sein ;-) 

.....Es ist mein Glaube, dass Niedrigdosis Mundinterferon eine vorteilhafte Therapie aller Grippeviren ist, nicht gerade die Belastung H1N1,“ sagte Dr. Joseph M. Cummins, Präsident und Vorstandsvorsitzende von ABI......

Antworten
Kleine_prinz:

;-))))

 
08.03.10 20:34
Amarillo signs licensing and supply agreement with Intas Pharmaceuticals
  

Posted on: Fri, 05 Mar 2010 09:43:20 EST

Mar 05, 2010 (Datamonitor via COMTEX) --

Amarillo Biosciences, a US-based biotechnology company, has signed a licensing and supply agreement with Intas Pharmaceuticals, an Indian pharmaceutical company.

Intas plans to launch a double-blind, placebo-controlled Phase III clinical trial of Amarillo Biosciences's (ABI) orally administered interferon-alpha lozenges in India by the end of March 2010. The study will include up to 520 patients with clinical signs and symptoms of influenza. Intas will pay ABI a royalty on net sales in India and Nepal after marketing approval is obtained.

The objective of the clinical trial planned in India is to determine the safety and efficacy of low dose oral interferon in reducing the severity of infection with influenza viruses such as H1N1.

Joseph Cummins, president and CEO of ABI, said: "Influenza viruses mutate to evade the effects of anti-viral drugs. Influenza viruses do not mutate to evade interferon, but instead they have a strategy to sabotage the host interferon system. By giving people interferon orally, we believe we can overcome this viral strategy. It is my belief that low-dose oral interferon will be a beneficial therapy of all influenza viruses, not just the H1N1 strain."

http://www.datamonitor.com Republication or redistribution, including by framing or similar means, is expressly prohibited without prior written consent. Datamonitor shall not be liable for errors or delays in the content, or for any actions taken in reliance thereon

For full details on (AMAR) AMAR. (AMAR) has Short Term PowerRatings at TradingMarkets. Details on (AMAR) Short Term PowerRatings is available at This Link.

http://www.tradingmarkets.com/news/stock-alert/...uticals-826341.html

Antworten
Kleine_prinz:

Amarillo Present Oral Interferon Study ;-))

 
25.03.10 15:59

Dr. Manfred Beilharz to Present Oral Interferon Study Findings at 3rd World Summit of Antivirals in Busan, Korea

Press Release Source: Amarillo Biosciences, Inc. On Tuesday March 23, 2010, 10:59 am EDT

AMARILLO, TX--(Marketwire - 03/23/10) - Amarillo Biosciences, Inc. (ABI) (OTC.BB:AMAR - News) today announced that Dr. Manfred Beilharz, Chair of Microbiology and Immunology, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia will make a presentation entitled, Low Dose Oral Type 1 IFN: A New Defense Against Colds and Flu, at the 3rd World Summit of Antiviral Summit Shelf in Busan, South Korea on July 31-August 3, 2010. Dr. Beilharz was one of the principal investigators of the study that tested ABI's oral interferon lozenges during the 2009 influenza season in Australia.

In the Phase 2 clinical trial conducted in Perth, Western Australia, 200 healthy volunteers were given placebo or ABI's low-dose oral interferon for prevention and treatment of naturally occurring colds and influenza. The study was funded by the Health Department of Western Australia. This double-blind, randomized trial showed that ABI's orally administered interferon lozenges were safe when taken daily for 16 weeks by subjects during the winter colds and flu season. The study found that subjects given interferon tended to more frequently report mild cold/flu symptoms, compared to subjects given placebo who more frequently reported moderate to severe symptoms. Additionally, subjects in the interferon group who received trivalent seasonal influenza vaccine prior to the study had a significantly lower incidence of influenza-like illness during treatment, compared to subjects in the placebo group who had been vaccinated.

The Phase 2 clinical trial in Perth, Australia was conducted under unprecedented circumstances. The trial was planned and designed before the pandemic H1N1 influenza was even known to exist, and the trial got underway just as Australia became an epicenter of the pandemic. Because of this, additional analyses are planned on the trial data to evaluate the treated subjects' responses to oral interferon during the pandemic as well as the interactions between vaccination status and H1N1 influenza infection. Testing of blood samples taken from the study volunteers for the presence of H1N1 influenza virus will be completed soon. Because it is unique, having coincided precisely with the pandemic, the trial should provide important and new information regarding the 2009 H1N1 pandemic that will be useful for designing future trials.

"The Perth trial has shown, by significant reduction of incidence of flu-like illness in treated subjects, that oral interferon increased the efficacy of the seasonal influenza vaccine for protection against pandemic H1N1 influenza. This is the first time that an influenza drug has been shown to enhance the efficacy of any human influenza vaccination. This finding is especially important because the trial demonstrated that the partial protection afforded by seasonal influenza vaccine against pandemic H1N1 could be significantly enhanced by the administration of oral interferon," said Dr. Beilharz.

Dr. Beilharz went on to comment, "The efficacy of oral interferon in reducing the severity of influenza symptoms, with or without vaccination, is likewise very important. Conversion of what would be severe influenza symptoms to milder symptoms by use of oral interferon may result in fewer hospitalizations, fewer complications, and potentially reduced mortality associated with severe and potentially Tamiflu-resistant influenza outbreaks. In summary, the trial results show that oral interferon is the right drug at the right time."

About Amarillo Biosciences
Amarillo Biosciences, Inc. is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 6% of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R&D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including influenza, hepatitis C, chronic cough, and opportunistic infections in patients who are HIV positive. The Company has invested nearly $40 million to establish oral interferon as a therapeutic agent. The majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the web at http://www.amarbio.com/.

Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" and "Item 7A. Qualitative and Quantitative Disclosures About Market Risk" of the Company's Form 10-K for the fiscal year ended December 31, 2008.

Contact:



Investor Relations:
Philippe Niemetz
PAN Consultants, Ltd.
e-mail:mailto:e-mail:p.niemetz@panconsultants.com
Tel: 800-477-7570; 212-344-6464
Fax: 212-618-1276
Joseph M. Cummins, DVM, PhD
Amarillo Biosciences, Inc.
e-mail:mailto:e-mail:jcummins@amarbio.com
Tel: 806-376-1741 x 13
Fax: 806-376-9301 http://finance.yahoo.com/news/...z-to-iw-2437432400.html?x=0&.v=1
Antworten
Kleine_prinz:

Amarillo startet in Deutschland ;-)))

 
31.05.10 10:44

http://finance.yahoo.com/news/...tary-iw-1791478615.html?x=0&.v=1

 

Amarillo Biosciences' Dietary Supplement for Dry Mouth Maxisal Launched in Germany

Dietary Ingredient Derived From Animals in Texas Feed Yards to Help Promote Health

Companies:

Press Release Source: Amarillo Biosciences, Inc. On Friday May 28, 2010, 8:55 am EDT

AMARILLO, TX--(Marketwire - 05/28/10) - Amarillo Biosciences, Inc. (ABI) (OTC.BB:AMAR - News) today announced that Maxisal, its dietary supplement to enhance salivary function, promote oral comfort and help relive dry mouth, has been launched in Germany (http://us.lrd.yahoo.com/_ylt=AoeGc56yCgvy8KYb77hVxJKtcq9_;_ylu=X3oDMTE2aXZ0bjNrBHBvcwMzBHNlYwNuZXdzYXJzdGFydARzbGsDd3d3bWF4aXNhbGRl/SIG=10r3tf2a9/**http%3A//www.maxisal.de/). Maxisal is marketed in Germany by ABI's licensee Egofocus OHG based in Darmstadt. The first target market in Germany is cancer patients. There are over 400 medications, including some oncology drugs, that cause dry mouth as a severe side effect. By taking Maxisal, cancer patients may be able to relieve at least one of the side effects of cancer therapy. Maxisal was first offered for sale after clinical studies in subjects with Sjogren's syndrome (characterized by dry eyes and dry mouth) reported that the ingredient in Maxisal significantly improved mouth comfort and decreased mouth and throat dryness.

"Based on the favorable reception Maxisal has met in the U.S. -- which we attribute to the product's clinical and safety benefits, as well as reasonable cost -- we fully expect that it will be successful in Germany," said Dr. Joseph Cummins, President and CEO, ABI.

Separately, the company announced that it has prepared a dietary ingredient for natural food distributors to market as a dietary supplement. The ingredient is derived from animals in the feed yards of the Texas Panhandle.

"After more than 30 years of experience testing cytokines, in animals and man, we have developed a novel dietary ingredient derived from ruminant animals," said Dr. Joseph Cummins. "We are seeking distributors of dietary supplements worldwide and have initiated discussions in the USA, China, and South America. The animal product will be available in June and revenues from both of the dietary supplements are expected to help the Company fund its FDA clinical trials of oral human interferon in influenza and hepatitis C," added Dr. Cummins.

About Amarillo Biosciences
Amarillo Biosciences, Inc. is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 6% of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R&D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including influenza, hepatitis C, chronic cough, and opportunistic infections in patients who are HIV positive. The Company has invested nearly $40 million to establish oral interferon as a therapeutic agent. The majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the web at http://www.amarbio.com/.

Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" and "Item 7A. Qualitative and Quantitative Disclosures About Market Risk" of the Company's Form 10-K for the fiscal year ended December 31, 2009.

Contact:



Investor Relations:
Philippe Niemetz
PAN Consultants, Ltd.
e-mail:p.niemetz@panconsultants.com
Tel: 800-477-7570; 212-344-6464
Fax: 212-618-1276
Joseph M. Cummins, DVM, PhD
Amarillo Biosciences, Inc.
e-mail:jcummins@amarbio.com
Tel: 806-376-1741 x 13
Fax: 806-376-9301
Antworten
Kleine_prinz:

Babel Fish übersetzung ;-)))

 
31.05.10 10:52

http://de.babelfish.yahoo.com/...p=en_de&btnTrUrl=%C3%9Cbersetzen

Diätetische Ergänzung der Amarillo-Biowissenschaften für trockenen Mund Maxisal startete in Deutschland

Diätetischer Bestandteil leitete von den Tieren in den Texas-Zufuhr-Yards ab, um zu helfen, Gesundheit zu fördern

Pressekommuniqué-Quelle: Amarillo Biosciences, Inc. am Freitag, dem 28. Mai 2010, 8:55 morgens EDT

AMARILLO, TX--(Marketwire - 05/28/10) - Amarillo Biosciences, Inc. (ABI) (OTC.BB: AMAR - Nachrichten) heute verkündet, dass Maxisal, seine diätetische Ergänzung, zum von Speichel- Funktion zu erhöhen, des Mundkomforts zu fördern und zu helfen, trockenen Mund wieder zu erleben, in Deutschland (www.Maxisal.de) gestartet worden ist. Maxisal wird in Deutschland vom Lizenznehmer Egofocus OHG vermarktet ABIS, das in Darmstadt angesiedelt wird. Der erste Zielmarkt in Deutschland ist Krebspatienten. Es gibt über 400 Medikationen, einschließlich einige Onkologiedrogen, die trockenen Mund als strenge Nebenwirkung verursachen. Indem sie Maxisal nehmen, können Krebspatienten in der Lage sein, ein von mindestens den Nebenwirkungen der Krebstherapie zu entlasten. Maxisal wurde zuerst für Verkauf angeboten, nachdem klinische Studien in den Themen mit Sjogrens dem Syndrom (gekennzeichnet durch trockene Augen und trockenen Mund) dass der Bestandteil Maxisal in erheblich verbessertem Mundkomfort und in verringerter Mund- und Kehletrockenheit berichteten.

„Gegründet auf der vorteilhaften Aufnahme Maxisal hat sich in den US getroffen -- welches wir dem klinischen Produkt und Sicherheitsnutzen zuschreiben, sowie angemessene Kosten -- wir erwarten völlig, dass es in Deutschland erfolgreich ist,“ sagten Dr. Joseph Cummins, Präsident und Vorstandsvorsitzende, ABI.

Separat verkündete die Firma, dass sie einen diätetischen Bestandteil vorbereitet hat, damit natürliche Nahrungsmittelverteiler als diätetische Ergänzung vermarkten. Der Bestandteil wird von den Tieren in den Zufuhryards des TexasPanhandle abgeleitet.

„Nachdem mehr als 30 Jahre Erfahrungsprüfung cytokines, in den Tieren und im Mann, wir einen neuartigen diätetischen Bestandteil entwickelt haben, der von den Wiederkäuern abgeleitet wird,“ sagte Dr. Joseph Cummins. „Wir suchen Verteiler der diätetischen Ergänzungen weltweit und haben Diskussionen in den USA, im Porzellan und im Südamerika eingeleitet. Das Tierprodukt ist im Juni vorhanden und Einkommen von beiden der diätetischen Ergänzungen werden erwartet, um der Firmakapital zu helfen seine FDA-klinischen Studien des menschlichen mündlichinterferon in Grippe und in Hepatitis C,“ addierter Dr. Cummins.

Über Amarillo-Biowissenschaften
Amarillo Biosciences, Inc. ist ein US-Biotechnologieunternehmenbetrieb in der globalen Teilhaberschaft mit der Hayashibara Gruppe, die auch 6% von Amarillo-Biowissenschaftanteilen hält und über $18 Million in den Darlehen, in den Bewilligungen und in den Billigkeits-Investitionen zur Verfügung gestellt hat. Der Primärfokus der Firma ist umfangreicher und laufender R&D in den Gebrauch von Niedrigdosis, mündlich ausgeübtes Interferon als Behandlung für eine Vielzahl von Bedingungen, einschließlich Grippe, Hepatitis C, chronischen Husten und opportunistische Infektion bei Patienten, die HIV-POSITIV sind. Die Firma hat fast $40 Million investiert, um Mundinterferon als therapeutisches Mittel herzustellen. Die Majorität jener Kapital wurden in den klinischen Studien in einer Bemühung, FDA-Zustimmung für Interferon zu erzielen investiert. Zusätzliche Information ist auf dem Netz bei http://www.amarbio.com/ vorhanden.

Außer den historischen Informationen, die hierin enthalten werden, sind die Sachen, die in dieser Pressenotiz beraten über werden, vorausschauende Aussagen, die Risiken und Ungewissheiten, einschließlich die Ungewissheiten miteinbeziehen, die auf Produktentwicklung, die Ungewissheiten bezogen werden, die auf der Notwendigkeit an regelndem bezogen werden und andere Regierungszustimmungen, Abhängigkeit auf eigener Technologie, Ungewissheit der Marktannahme anderen von des Munddes interferon oder von anderer Anwärter des Produktes der Firma und riskiert gelegentlich einzeln aufgeführt in den Archivierungen der Firma mit der Börsenaufsichtsbehörde. Insbesondere sehen Sie „Beschreibung des Einzelteil-1. des Geschäfts“ und „des Einzelteils 7A. Qualitative und quantitative Freigabe über Konjunkturrisiko“ der Form 10-K der Firma für das Finanzjahr beendete 31. Dezember 2009.

Kontakt:



Beziehungen zwischen den Investoren:
Philippe Niemetz
WANNE Berater, Ltd.
mailto:e-mail:p.niemetz@panconsultants.com
Telefon: 800-477-7570; 212-344-6464
Telefax: 212-618-1276
Joseph M. Cummins, DVM, PhD
Amarillo Biosciences, Inc.
mailto:e-mail:jcummins@amarbio.com
Telefon: 806-376-1741 x 13
Telefax: 806-376-9301
Antworten
Chalifmann3:

HÄÄÄ ??!!

 
31.05.10 11:12
Was'n das für ne Schrottaktie ? "....Amarillo" ??!!?? Leute,lasst bloss die finger von diesem OTC-Dreck,diese company ist nicht nur nichts wert,sondern auch noch pleite,das dürfte an DD genügen !!

MFG
Chali
Antworten
Kleine_prinz:

Hier der Link zu (D) Homepage ;-)

 
31.05.10 11:15
http://66.196.80.202/babelfish/translate_url_content?.intl=de&lp=en_de&trurl=http%3a%2f%2fwww.maxisal.de%2f  Hinweise zur Anwendung

Verwenden Sie MAXISAL 3 x täglich bitte immer ZWISCHEN Höhle Mahlzeiten, indem Sie MAXISAL langsam lutschen. Kauen Oder Schlucken von MAXISAL bringt KEINEN Erfolg. DAS Lutschen der kleinen Tablette kann BIS zu 45 andauern Minuten. Nach Wir-amerikanischen Studien ein vielen Patienten nimmt sterben Wirksamkeit von MAXISAL mit der Häufigkeit der Anwendung zu. Nach 6-wöchiger Anwendung Hut jeder zweite geduldiges gute Speichelproduktion, sterben bei weiterer Einnahme anhält.

Wir wünschen Ihnen viel Erfolg MIT MAXISAL
und eine gute Gesundheit!

Wichtige Hinweise: Als diätetisches Lebensmittel für besondere medizinische Zwecke (ergänzend bilanzierte Diät) ist MAXISAL unter ärztlicher Aufsicht zu verwenden. MAXISAL ist kein vollwertiges Lebensmittel. Einnahme ist kein sterben Ersatz für eine abwechslungsreiche und ausgewogene Ernährung, sowie eine gesunde Lebensweise. Aufgrund der besonderen Zweckbestimmung Wird von den, nach Anlage 6 zu, das § 14 b DiätV Mengen festgelegten, ein Nährstoffen abgewichen. Außerhalb der Reichweite von Kindern aufbewahren.

Zutaten

98% kristalline wasserfreie Maltose, Trennmittel Magnesiumstearat

Antworten
zettma:

Wo steht das die Pleite sind???

 
01.06.10 08:48
Antworten
Kleine_prinz:

Amarillo Biosciences Hepatitis C ;-))

 
09.11.10 22:21
Amarillo Biosciences Issues Progress Report
 
Press Release Source: Amarillo Biosciences, Inc. On Tuesday November 9, 2010, 3:44 pm

AMARILLO, TX--(Marketwire - 11/09/10) - Amarillo Biosciences, Inc. (ABI) (OTC.BB:AMAR - News) today issued the following Progress Report:

 

  • Hepatitis C: CytoPharm, Inc., ABI's strategic partner in Taiwan is funding a Phase 2 clinical trial of 165 patients with chronic hepatitis C virus infection. As of the end of October 2010, 124 patients have already been enrolled with full enrollment expected by early 2011. The aim of the trial is to reduce the virologic relapse rate for those patients who have completed the standard combination therapy for hepatitis C, which consists of high dose injectable interferon alpha and Ribavirin. Although most patients respond to the standard therapy, up to 50% of those with certain viral genotypes relapse after treatment. Patients in the study will receive one of two different daily doses of ABI's human interferon alpha lozenges or placebo for 24 weeks, followed by untreated observation for 24 weeks to check for relapse. Preliminary results from this important study are expected to be available before the end of next year.

     
  • Influenza: In addition to its hepatitis C study, CytoPharm will be funding a study of ABI's interferon-alpha lozenges in the treatment of influenza. The study, which has been approved by the Taiwanese Department of Health, will start in January 2011. Half of the patients with confirmed influenza A infection will be assigned to 5 days of twice daily treatment with interferon lozenges and half will receive placebo. All of the patients will also receive standard treatment with Tamiflu. The aim of the study is to determine if the combination of Tamiflu plus oral interferon is superior to Tamiflu alone in the treatment of influenza.

     
  • Scientific journal publication on interferon and influenza: The Company's technology will be featured in an upcoming issue of the scientific journal, Expert Opinion on Biological Therapy (EOBT). The editors of the EOBT independently commissioned Dr. Manfred Beilharz to write a review article, which is titled: "Low dose oral interferon alpha: has its time finally come?" This article discusses the various studies in which ABI's low dose interferon-alpha lozenges has been used to successfully treat various human diseases, with a focus on influenza. Dr. Beilharz was one of the investigators of a study in which the Company's interferon-alpha lozenges were found to reduce the incidence of moderate to severe febrile acute respiratory illness (i.e. cold/flu with a fever) when taken daily by healthy volunteers during the winter cold/flu season in Australia.

     

 

About Amarillo Biosciences
Amarillo Biosciences, Inc. is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 5.4% of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R&D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including influenza, hepatitis C, chronic cough, and opportunistic infections in patients who are HIV positive. The Company has invested nearly $40 million to establish oral interferon as a therapeutic agent. The majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the web at http://www.amarbio.com/.

Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" and "Item 7A. Qualitative and Quantitative Disclosures About Market Risk" of the Company's Form 10-K for the fiscal year ended December 31, 2009.

Contact:



Investor Relations:
Philippe Niemetz
PAN Consultants, Ltd.
e-mail:p.niemetz@panconsultants.com
Tel: 800-477-7570; 212-344-6464
Fax: 212-618-1276
Joseph M. Cummins, DVM, PhD
Amarillo Biosciences, Inc.
e-mail:jcummins@amarbio.com
Tel: 806-376-1741 x 13
Fax: 806-376-9301
 

http://finance.yahoo.com/news/...iosciences-Issues-iw-1618829834.html

Antworten
Kleine_prinz:

Totgesagte leben länger ;-)))

 
15.11.10 09:49

CLINICAL TRIALSAmarillo Bioscience - ein aussichtsreicher Wert! 9094307Amarillo Bioscience - ein aussichtsreicher Wert! 9094307Amarillo Bioscience - ein aussichtsreicher Wert! 9094307

AMAR has three active human clinical development programs for oral interferon.

 

Preclinical

Phase 1

Phase 2

Phase 3

Anticipated
Approval

Influenza#99cccc">#99ccff; font-family: arial, helvetica, sans-serif; font-size: 12pt"> #99cccc">#99ccff; font-family: arial, helvetica, sans-serif; font-size: 12pt"> #99cccc">

#99ccff; font-family: arial, helvetica, sans-serif"> 

 

2013

Chronic Cough (COPD)#99cccc"> #99cccc"> #99cccc">  

2014

Hepatitis C#99cccc"> #99cccc"> #99cccc">  

2014

Influenza

Clinical studies have demonstrated that low doses of intranasal or oral interferon are safe and effective at preventing or treating influenza. In the former Soviet Union, approximately 14,000 people participated in controlled studies of placebo versus interferon treatment during a natural outbreak of Hong Kong influenza. Interferon (about 128 units) or placebo was dripped into the nose daily for 5 days starting about the time of the first reported influenza cases. Interferon treatment significantly reduced the number of influenza cases (P<0.01 for all age groups).

 Amarillo Bioscience - ein aussichtsreicher Wert! 9094307

The University of Western Australia received a grant from the Department of Health, Government of Western Australia and in May 2009 started a Phase 2 clinical study of oral interferon as prevention/treatment of respiratory illnesses, including influenza, in Perth, Australia. Two hundred (200) healthy volunteers were enrolled to take oral IFN or placebo lozenges once daily for 16 weeks.  Once per week, the study volunteers completed a questionnaire detailing the severity of any cold/flu symptoms experienced, any medications taken, number of days of work missed, etc.  The aim of the study was to determine whether the volunteers who took oral IFN would experience fewer respiratory illnesses and/or less severe symptoms during the 2009 winter cold/flu season in Australia.

The study found that volunteers who took oral interferon had less severe cold/flu symptoms, compared to volunteers who received placebo. Significantly fewer volunteers in the interferon group who had been vaccinated against seasonal influenza had an episode of influenza-like illness during the study, compared to vaccinated volunteers in the placebo group. Additionally, volunteers over the age of 50 (high risk for influenza) experienced fewer episodes of influenza-like illness if they took interferon during the study, compared to those who received placebo.

Follow-up studies are planned during the 2010/11 influenza season. In the US, 200 patients in the third day of a confirmed influenza A/B infection and moderate to severe fever and flu-like symptoms will be treated twice daily for 4 days to see if oral IFN can reduce the duration and severity of influenza illness, compared to placebo.

In Taiwan, 60 patients being treated with Tamiflu for influenza A infection of less than 48 hours’ duration will be randomly assigned to co-treatment with oral IFN or placebo. The aim of the study is to examine whether the combination of oral IFN and Tamiflu is superior to Taimflu alone in the treatment of influenza illness.

For more information on this study, please visit: http://clinicaltrials.gov/ct2/show/NCT00895947 

or contact Martin Cummins.

Chronic Cough-COPD

In a pilot study, 5 of 6 patients with idiopathic pulmonary fibrosis (IPF) reported significant relief of their chronic cough after taking oral interferon.  Reduction in cough resulted in better sleep and an improved quality of life for these IPF patients.

Texas Tech University is currently funding a proof-of-concept study to evaluate oral interferon in the treatment chronic cough in COPD and IPF patients. This experimental clinical study will be a Phase 2 randomized, double-blind, placebo-controlled, parallel trial in which 40 eligible volunteers with IPF- or COPD-associated chronic cough will be randomly assigned to one of two groups in equal numbers to receive either interferon alpha or placebo. Treatment will be given three times daily for 4 weeks, and patients will be followed for 4 weeks post-treatment to assess durability of response. The study will evaluate the ability of interferon alpha to reduce the frequency and severity of chronic cough in COPD patients.

For more information or to participate in this study, please visit: http://clinicaltrials.gov/ct2/show/NCT00690885 

or contact: Martin Cummins.

Hepatitis C

CytoPharm, Inc., AMAR’s licensee for Taiwan and China, launched a Phase 2, placebo-controlled, dose-ranging study of 165 hepatitis C virus-infected patients in Taiwan in the second quarter of 2009.  The study, which has been approved by both the US FDA and the Taiwanese Department of Health, is designed to test the ability of oral interferon to reduce the virologic relapse rate of patients who have completed standard therapy with pegylated interferon plus ribavirin.  Treatment time is 6 months with 6 months of post treatment observation.  Preliminary results are expected in the second half of 2011.

For more information on this study, please visit: http://clinicaltrials.gov/ct2/show/NCT00695019

or contact: Martin Cummins.

Antworten
Kleine_prinz:

Maxisal for Indian Market ;-))

 
16.11.10 16:51
Amarillo Biosciences to Supply Zydus Cadila, India's Fifth Largest Pharmaceutical Company, With Dietary Supplement Maxisal for Indian MarketAmarillo Bioscience - ein aussichtsreicher Wert! 9105366
Press Release Source: Amarillo Biosciences, Inc. On Tuesday November 16, 2010, 10:04 am

AMARILLO, TX--(Marketwire - 11/16/10) - Amarillo Biosciences, Inc. (ABI) (OTC.BB:AMAR - News) today announced that it has signed a supply agreement with Zydus Cadila, the fifth largest pharmaceutical company in India, with projected worldwide sales of $1 billion in fiscal year 2010 and $3 billion in 2015. Under this agreement, Zydus will market ABI's dietary supplement Maxisal in India and Nepal. Maxisal enhances salivary function, promotes oral comfort and helps relieve dry mouth.

ABI initially launched Maxisal in the United States after clinical studies in subjects with Sjögren's syndrome (characterized by dry eyes and dry mouth) found that the active ingredient in Maxisal significantly improved mouth comfort and decreased mouth and throat dryness. Maxisal is marketed in Germany by ABI's licensee Egofocus OHG based in Darmstadt.

"Based on the favorable reception Maxisal has met in the U.S., -- which we attribute to the product's clinical benefits and reasonable cost -- we fully expect that it will be successful in India. We are delighted that Zydus Cadila has agreed to market Maxisal and are hopeful that success in India and Nepal will lead them to expand Maxisal into some of the more than 50 other countries in which they currently market products," said Dr. Joseph Cummins, President and CEO, ABI.

About Amarillo Biosciences
Amarillo Biosciences, Inc. is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 5.4% of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R&D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including influenza, hepatitis C, chronic cough, and opportunistic infections in patients who are HIV positive. The Company has invested nearly $40 million to establish oral interferon as a therapeutic agent. The majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the web at http://www.amarbio.com/.

About Zydus Cadila
Zydus Cadila is an innovative global pharmaceutical company that discovers, develops, manufactures and markets a broad range of healthcare products. The group's operations range from API to formulations, animal health products and cosmeceuticals. Headquartered in the city of Ahmedabad in India, the group has global operations in four continents spread across USA, Europe, Japan, Brazil, South Africa and 25 other emerging markets. In its mission to create healthier communities globally, Zydus Cadila delivers wide ranging healthcare solutions and value to its customers. With over 11,000 employees worldwide, a world-class research and development centre dedicated to discovery research and eight state-of-the-art manufacturing plants, the group is dedicated to improving people's lives. Additional information is available on the web at http://www.zyduscadila.com/.

Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" and "Item 7A. Qualitative and Quantitative Disclosures About Market Risk" of the Company's Form 10-K for the fiscal year ended December 31, 2009.

Contact:



Investor Relations:
Philippe Niemetz
PAN Consultants, Ltd.
e-mail: p.niemetz@panconsultants.com
Tel: 800-477-7570; 212-344-6464
Fax: 212-618-1276
Joseph M. Cummins, DVM, PhD
Amarillo Biosciences, Inc.
e-mail: jcummins@amarbio.com
Tel: 806-376-1741 x 13
Fax: 806-376-9301
 

http://finance.yahoo.com/news/...s-to-iw-3050834167.html?x=0&.v=1

Antworten
Kleine_prinz:

Amarillo gibt gas + 40%

 
17.11.10 19:39
Antworten
Kleine_prinz:

Wow +62,50% :-)))))

 
17.11.10 20:18
Antworten
Kleine_prinz:

Maxisal mehr erweitern 50 andere Länder ;-))

 
19.11.10 09:50

http://sify.com/finance/zydus-cadila-to-market-amarillo-s-maxisal-in-india-and-nepal-news-equity-klsblsacjij.html

Zydus cadila to market Amarillo's Maxisal in india and nepal

BS Reporter  | 2010-11-18 01:11:00


Ahmedabad based pharma major Zydus Cadila has entered into an agreement with US based Amarillo Biosciences Inc(ABI to market ABI's dietary supplement Maxisal in India and Nepal.

Nasdaq listed ABI has informed the stock exchange in this regard. Maxisal enhances salivary function,promotes oral comfort and helps relieve dry mouth. Amarillo had initially launched Maxisal in the US market after clinical studies in subjects with gren's syndrome (characterised by dry eyes and dry mouth) found that the active ingredient in Maxisal significantly improved mouth comfort and decreased mouth and throat dryness.

Maxisal is marketed in Germany by ABI's licensee Egofocus OHG based in Darmstadt.

"Based on the favorable reception Maxisal has met in the US, which we attribute to the product's clinical benefits and reasonable cost, we fully expect that it will be successful in India. We are delighted that Zydus Cadila has agreed to market Maxisal and are hopeful that success in India and Nepal will lead them to expand Maxisal into some of the more than 50 other countries in which they currently market products," Joseph Cummins, President and CEO, ABI said in a statement. Pankaj Patel, chairman and managing director of Zydus Cadila was unavailable for a comment. Amarillo Biosciences, Inc. is a US based biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 5.4 per cent of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. Ahmedabad based Intas Pharmaceuticals Limited (Intas) had entered into a strategic partnership with Amarillo Biosciences, Inc (ABI) in December last year, whereby Intas will sponsor clinical trials of ABI's orally administered interferon-alpha lozenges for influenza, and could also be used in combating the H1N1 virus for swine flu. Intas will pay ABI a royalty on net sales after marketing approval is obtained in India.

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More HeadlinesAll About: Zydus Cadila, Pharma sector, Amarillo Biosciences Inc, Joseph Cummins, Maxisal, ABI, Alpha, Biotechnology, Intas Pharmaceuticals Limited, Hayashibara Group, Amarillo Biosciences Inc., Egofocus OHG

Antworten
zettma:

...

 
22.11.10 15:11

Bin auch schon länger hier investiert. Bin auch der Überzeugung, dass wir hier noch viel Freude haben werden.

Wie schon gesagt: Todgesagte leben länger!!!

Antworten
Kleine_prinz:

Amarillo scheint immer mehr gefragt zu sein ;-)

 
30.11.10 16:14
Antworten
zettma:

Ja

 
30.11.10 16:34

da werden wir noch viel Freude haben!!!

Antworten
Kleine_prinz:

Phase 2 Hepatitis C Trial ;-))

 
14.12.10 18:26

Amarillo Biosciences Announces Completion of Patient Enrollment in Phase 2 Hepatitis C Trial

 

Press Release Source: Amarillo Biosciences, Inc. On Tuesday December 14, 2010, 11:08 am EST

AMARILLO, TX--(Marketwire - 12/14/10) - Amarillo Biosciences, Inc. (ABI) (OTC.BB:AMAR - News) today announced that enrollment in a Phase 2 clinical trial of 165 patients with chronic hepatitis C virus infection is now complete. The clinical trial is being conducted in Taiwan and funded by ABI's strategic partner, CytoPharm, Inc. The aim of the study is to reduce the virologic relapse rate for those patients who have successfully completed standard combination therapy for hepatitis C, which consists of injectable interferon alpha and Ribavirin.

Many patients with hepatitis C are found to be virus-free at the end of standard therapy, but up to half of those with certain viral genotypes relapse in the six months following treatment, once again becoming positive for hepatitis C virus. There are currently no FDA-approved medications shown to reduce the relapse rate for hepatitis C patients, so there is a clear medical need for effective new therapies.

All patients enrolled in this trial first completed standard therapy and were found to be negative for hepatitis C virus. The patients were then assigned to one of two different daily doses of ABI's human interferon alpha lozenges or placebo for 24 weeks, followed by untreated observation for 24 weeks to check for relapse. All patients are scheduled to complete the untreated observation phase by December 2011, and final results from this important study are expected to be available by the end of next year.

About Amarillo Biosciences
Amarillo Biosciences, Inc. is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 5.4% of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R&D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including influenza, hepatitis C, chronic cough, and opportunistic infections in patients who are HIV positive. The Company has invested nearly $40 million to establish oral interferon as a therapeutic agent. The majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the web at http://www.amarbio.com/.

Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" and "Item 7A. Qualitative and Quantitative Disclosures About Market Risk" of the Company's Form 10-K for the fiscal year ended December 31, 2009.

http://finance.yahoo.com/news/...nces-iw-3725040897.html?x=0&.v=1

Antworten
Kleine_prinz:

Amarillo Biosciences Announces ;-)))

 
05.01.11 23:00
Amarillo Biosciences Announces Study of Oral Interferon and Tamiflu for Treatment of InfluenzaAmarillo Bioscience - ein aussichtsreicher Wert! 9443465

http://finance.yahoo.com/news/...nces-iw-1916973722.html?x=0&.v=1

Antworten
Kleine_prinz:

Amarillo Biosciences and Oasis Diagnostics(R) ;-)

 
18.01.11 10:51
Amarillo Biosciences and Oasis Diagnostics(R) Sign License and Supply Agreement for Dietary Supplement Maxisal(R)

 

Press Release Source: Amarillo Biosciences, Inc. On Friday January 14, 2011, 7:00 am EST

AMARILLO, TX--(Marketwire - 01/14/11) - Amarillo Biosciences, Inc. (ABI) (OTC.BB:AMAR - News) and Oasis Diagnostics® Corporation today announced that they have entered into an agreement under which Oasis will exclusively market Maxisal®, ABI's dietary supplement for enhancement of salivary function, promotion of oral comfort and relief of dry mouth, in North, Central and South America, China and Taiwan.

Oasis, a salivary diagnostics and genomics company based in Vancouver, WA, plans to expand on ABI's current marketing efforts by exploring new potential markets for Maxisal® in patients undergoing kidney dialysis and chemotherapy, those with dryness-related sexual dysfunction, and individuals with burning-mouth syndrome and other dryness-related conditions. Current estimates put the number of dry mouth sufferers in the US at 25 million.

Maxisal® is currently marketed by ABI's licensees Egofocus OHG in Germany and Zydus Cadila in India. The first target market in Germany and India is cancer patients. There are over 400 medications, including some oncology drugs that cause dry mouth as a severe side effect. By taking Maxisal®, cancer patients may be able to relieve at least one of the unpleasant side effects associated with cancer therapy.

Maxisal® was first offered for sale in the US after clinical studies in subjects with Sjogren's syndrome (characterized by dry eyes and dry mouth) reported that the active ingredient in Maxisal® significantly improved mouth comfort and decreased mouth and throat dryness.

"Clinical data has confirmed the beneficial effects of Maxisal in people experiencing dry mouth. With its widespread knowledge and expertise in salivary diagnosis and treatment, and its expansive network of contacts in the oral health arena, I fully expect Oasis to be successful at marketing Maxisal for individuals experiencing the unpleasant and potentially dangerous symptom of dry mouth," said Dr. Joseph Cummins, President and CEO of ABI.

"We are extremely happy and excited to have executed this license agreement with ABI. We feel that Maxisal® fits extremely well into our portfolio of novel tools for oral health and will open up new windows of opportunity for our growing company and its partners," said Dr. Paul Slowey, CEO of Oasis Diagnostics® Corporation.

About Amarillo Biosciences
Amarillo Biosciences, Inc. is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 6% of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R&D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including influenza, hepatitis C, chronic cough, and opportunistic infections in patients who are HIV positive. The Company has invested nearly $40 million to establish oral interferon as a therapeutic agent. The majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the web at http://www.amarbio.com/.

About Oasis Diagnostics
Oasis Diagnostics® Corporation is an emerging Company focused on two core areas of the in vitro diagnostic market -- saliva based diagnostics and genomics. Over the past eight years the Company has assembled a portfolio of proprietary devices and tools for the standardized collection of saliva, immediate disease testing from saliva and the collection of DNA from saliva specimens. Oasis' non-invasive collection and testing technologies address the three main segments of the IVD market -- molecular diagnostics, rapid, point-of-care testing and diagnostics performed in the laboratory, and may be applied to a variety of areas including infectious diseases [including tuberculosis and HIV], steroid hormones for general wellness, oncology, immune response, cardiovascular disease and many others. Additional information is available on the web at http://www.4saliva.com/.

Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" and "Item 7A. Qualitative and Quantitative Disclosures About Market Risk" of the Company's Form 10-K for the fiscal year ended December 31, 2009.

http://finance.yahoo.com/news/...s-and-iw-549387673.html?x=0&.v=1

Antworten
Kleine_prinz:

Amarillo CEO Does Live Interview :-)

 
18.01.11 10:54

Amarillo Biosciences' CEO Does Live Interview on ChartPoppers.com

Press Release Source: Amarillo Biosciences, Inc. On Monday January 17, 2011, 7:00 am EST

AMARILLO, TX--(Marketwire - 01/17/11) - Amarillo Biosciences, Inc. (ABI) (OTC.BB:AMAR - News) -- ABI announced today that a new audio interview with ChartPoppers.com (http://chartpoppers.com) is now available. The interview can be viewed at http://ChartPoppers.com/iReports.

Amarillo Biosciences, Inc. (OTC.BB:AMAR - News) is developing low-dose oral interferon for human and animal health. The product is safe, inexpensive, stable at room temperature, easy-to-administer and modulates the immune system by helping regulate interferon sensitive genes. The company asserts that low dose oral interferon can achieve many of the benefits of high dose injectable interferon without the toxicity reported by most patients given high dose injectable interferon.

In the interview, the CEO notes: "Our new license and supply agreement with Oasis Diagnostics is expected to generate revenues this year." To listen to the entire interview visit: http://ChartPoppers.com/iReports.

About ChartPoppers
ChartPoppers.com is a small-cap research and investment commentary provider. ChartPoppers.com strives to provide a balanced view of many promising small-cap companies that would otherwise fall under the radar of the typical Wall Street investor. We provide investors with an excellent first step in their research and due diligence by providing daily trading ideas, and consolidating the public information available on them. For more information on ChartPoppers, please visit http://ChartPoppers.com/ireports.

ChartPoppers.com Disclosure
ChartPoppers.com is not a registered investment advisor and nothing contained in any materials should be construed as a recommendation to buy or sell any securities. ChartPoppers.com is a Web site wholly owned by Seo Freisin, Inc. ChartPoppers.com nor its affiliates have a beneficial interest in the mentioned company; nor have they received compensation of any kind for any of the companies listed in this communication. Please read our report and visit our Web site, ChartPoppers.com, for complete risks and disclosures.

About Amarillo Biosciences
Amarillo Biosciences, Inc. is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 6% of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R&D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including influenza, hepatitis C, chronic cough, and opportunistic infections in patients who are HIV positive. The Company has invested nearly $40 million to establish oral interferon as a therapeutic agent. The majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the web at http://www.amarbio.com/.

Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" and "Item 7A. Qualitative and Quantitative Disclosures About Market Risk" of the Company's Form 10-K for the fiscal year ended December 31, 2009.

http://finance.yahoo.com/news/...Does-iw-1804694085.html?x=0&.v=1

Antworten
Kleine_prinz:

Amarillo hohes Volumen in USA ;-))

 
01.02.11 12:50

362.699 stück

Es scheint das bald gute News  kommen..

http://www.ariva.de/quote/simple.m?secu=241951

http://finance.yahoo.com/q?s=AMAR.OB

Antworten
Kleine_prinz:

Heute mal wieder hohes Volumen und +33,22% ;-))

 
03.02.11 22:17
Antworten
Kleine_prinz:

generate 20-50 mil in sales for Amar?

 
05.02.11 13:51

Herpes, Genital Warts, COPD, IPF all had no cure available till now.    The herpes/genital warts angle will generate 20-50 mil in sales for Amar  within a year or two.

 

FAQ's .
    .
Frequently Asked Questions
Q. What is Virapress?
A.   Virapress is a proprietary formulation of naturally occurring  immunomodulation agents, known as cytokines, such as interleukins and  interferon that are produced by all healthy animals.   These cytokines,  classified as proteins, regulate the body’s immune response to viral  outbreaks and autoimmune illnesses.

Q.   Is Virapress safe to take?
A. Yes.   The effectiveness of Virapress against viral-based and  autoimmune illnesses has been tested in studies over a 30 year period  and while the product has been found to be effective, no cases of  adverse side effects have been reported.   Since Virapress is comprised  of immunomodulation agents found in meat, as detailed above, the body  accepts the Virapress formulation and therefore no adverse side effects  are produced.

Q. How do I know that Virapress has the desired active ingredients?
A. The exclusive supplier of active immunomodulation agents for  Virapress is Amarillo Biosciences, run by Dr. Joseph Cummings, the  undisputed scientific expert on low-dose alpha interferon.   All batches  of bovine extract supplied to produce Virapress are tested and  documented to be safe from impurities and to have the desired strength  of active ingredients.

Q. How can Virapress help me?


A.   If you suffer from any viral based illness such as Idiopathic  Pulmonary Fibrosis, Shingles, Oral or Genital         Warts, or  Mononucleosis, to name a few, Virapress may improve or even eliminate  your symptoms.   The ingredients in Virapress work by stimulating the  body’s immune system sufficiently so the body is able to naturally  combat the virus.

Q.   Is Virapress only for combating viruses?
A.   No! Virapress is also effective against autoimmune disorders such  as IPF, COPD, Asthma, Emphysema, Bechet’s Disease, and Sjogren ’s  syndrome, to name a few.   In these cases, Virapress regulates the  body’s immune response to the invading illness, thus reducing or  eliminating the illness which has been caused by an overactive immune  system attacking healthy cells.

Q. Does Virapress work the same for everyone?
A.   Results may vary depending on several factors, such as the severity  and/or longevity of the disorder, as well as other health issues, such  as lifestyle, that may exacerbate the disease.   However, Virapress has  either lessened symptoms or stopped the progression of the disease in  the vast majority of people who have taken the product.   Before  deciding to try Virapress, we encourage you to refer to our web site, www.virapress.com and also the website featuring our product, www.healthnewslink.com  , and familiarize yourself with the product case studies and also read  testimonials of real people who have taken the product, and then decide  if Virapress is right for you.

Antworten
Kleine_prinz:

Interessanter Artikel über

 
05.02.11 13:54

 low-dose oral alpha interferon 

 

healthnewslink.com/...catid=77:personal-stories&Itemid=153

Antworten
Kleine_prinz:

Lizenz und Versorgungsabkommen ;-))

 
06.02.11 13:10

Form 8-K for AMARILLO BIOSCIENCES INC

4-Feb-2011

Other Events

 


Item 8.01 Other Events.

Amarillo Biosciences, Inc. (ABI) has license and supply agreements with Hayashibara Biochemical Laboratories (HBL), the sole supplier of human interferon alpha (IFN?) and anhydrous crystalline maltose (ACM) to the Company. HBL is part of the Hayashibara Group of companies, which announced on February 2, 2011 on its website in Japan that it had filed a petition for corporate reorganization with the Tokyo District Court.

In a letter to customers dated February 2, 2011, Mr. Hideki Matsushima, who has been appointed by the Tokyo District Court to be the provisional administrator of HBL, made the following statements, "&#65533;I would like to inform you that we will endeavor to supply our products to our customers in a stable fashion. We believe that we will be able to ensure a stable supply of our products, since we have been permitted by the Tokyo District Court to pay our debts to our suppliers related to the purchase of raw materials for our products, on the condition that our suppliers will continue to do business with us under the pre-existing payment terms and conditions."

Based on these statements from Mr. Matsushima, ABI does not expect any disruption in the supply of IFN? or ACM from HBL.

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, hereunto duly authorized.

DATE: February 4, 2011.

AMARILLO BIOSCIENCES, INC.

By: /s/ Joseph M. Cummins
Joseph M. Cummins, Chairman of the Board, President and Chief Executive Officer

 

http://biz.yahoo.com/e/110204/amar.ob8-k.html

 


Antworten
Kleine_prinz:

Amarillo als virapress

 
06.02.11 20:20

Lieferant könnte sich jetzt sehr positiv Entwikeln ;-)

www.virapress.com

Antworten
Kleine_prinz:

Und weiter gehts +18,18% ;-)))

 
07.02.11 16:19
Kleine_prinz:

Reasons to buy Fibrosis - Pipeline Assessment

 
15.02.11 16:09

© Reportlinker PRWire 2011 - By Roger Miller
15.02.2011 11:24:24

 

(live-PR.com) - Reportlinker.com announces that a new market research report related to the Pathology industry is available in its catalogue.

More information regarding this report:Idiopathic Pulmonary Fibrosis - Pipeline Assessment and Market Forecasts to 2017

http://www.reportlinker.com/p0240277/Idiopathic-Pulmonary-Fibrosis-Pipeline-Assessment-and-Market-Forecasts-to-2017.html#utm_source=LivePR&utm_medium=pr&utm_campaign=LivePR

Idiopathic Pulmonary
 
AICS FIELD INTERVIEWER : Meet Barry

http://www.youtube.com/...79739&kw=market%20research%20interviews

 

Fibrosis - Pipeline Assessment and Market Forecasts to 2017

Summary

GlobalData’s pharmaceutical and healthcare report, “Idiopathic Pulmonary Fibrosis - Pipeline Assessment and Market Forecasts to 2017” is an essential source of information and analysis on the global idiopathic pulmonary fibrosis market. The report identifies the key trends shaping and driving the global idiopathic pulmonary fibrosis market. The report also provides insight on the prevalent competitive landscape and the emerging players expected to bring significant shift in the market positioning of the existing market leaders. Most importantly, the report provides valuable insight on the pipeline products within the global idiopathic pulmonary fibrosis sector. This report is built using data and information sourced from proprietary databases, primary and secondary research and in house analysis by GlobalData’s team of industry experts.

The global Idiopathic Pulmonary Fibrosis (IPF) market was valued at $88m in 2009. It is expected to increase with a compound annual growth rate (CAGR) of 23% from $88m in 2009 to $462m by 2017. Earlier, the IPF market was underserved due to a lack of approved products. In October 2008, the Japanese manufacturer Shionogi received approval for Pirespa in Japan. It is under regulatory review for approval in the US and EU. The expected increase in sales is due to the expected approval of Pirespa in the US and the EU and also the expected launch of Tracleer and Letiaris. Growth in the IPF market is being driven by the sales of Pirespa, off-label drug use and the anticipated approval of Letiaris and Tracleer. Gilead’s Letiaris and Actelion’s Tracleer are the most anticipated molecules in the IPF market.

Scope

The report provides information on the key driver and challenges of the idiopathic pulmonary fibrosis market. Its Scope includes:
- Annualized global idiopathic pulmonary fibrosis market revenues data from 2001 to 2009, forecast forward for eight years to 2017.
- Pipeline analysis data providing a split across the different phases, mechanisms of action being developed and emerging trends. Key classes of mechanism of action include enzyme inhibitors, protein inhibitors, endothelin A antagonists, combination therapy, TNF alpha antagonists, platelet aggregation inhibitors, interferon alpha, interleukin inhibitors, immunosuppresants, growth hormone inhibitors, gene therapy, LPA1 receptor antagonists, tumor growth factor inhibitors and NK-1 antagonists.
- Analysis of the current and future market competition in the global idiopathic pulmonary fibrosis market. Key market players covered are Gilead Sciences, Actelion Ltd., Amgen Inc., InterMune Inc. and Amarillo Biosciences.
- Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.
- Key topics covered include strategic competitor assessment, market characterization, unmet needs and the implications for the future market associated with idiopathic pulmonary fibrosis therapeutics.

Reasons to buy

The report will enhance your decision making capability in a rapid and time sensitive manner. It will allow you to:
- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies and by identifying the companies with the most robust pipeline.
- Develop business strategies by understanding the trends shaping and driving the global idiopathic pulmonary fibrosis market.
- Drive revenues by understanding the key trends, innovative products and technologies, market segments and companies likely to impact the global idiopathic pulmonary fibrosis market in future.
- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain the competitive advantage.
- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.
- What’s the next big thing in the global idiopathic pulmonary fibrosis market landscape? – Identify, understand and capitalize. (rlk1-2011-02-15) olp

1 Table of contents 3
1.1 List of Tables 5
1.2 List of Figures 5
2 Global Idiopathic Pulmonary Fibrosis Market: Market Characterization 6
2.1 Overview 6
2.2 Idiopathic Pulmonary Fibrosis Market Size 6
2.3 Idiopathic Pulmonary Fibrosis Market Forecast and CAGR 6
2.4 Drivers and Barriers for Idiopathic Pulmonary Fibrosis Market 8
2.4.1 Drivers for Idiopathic Pulmonary Fibrosis Market 8
2.4.2 Barriers for Idiopathic Pulmonary Fibrosis Market 9
2.5 Opportunity and Unmet Need 10
2.6 Key Takeaway 11
3 Idiopathic Pulmonary Fibrosis Market: Competitive Assessment 13
3.1 Overview 13
3.2 Strategic Competitor Assessment 13
3.3 Profiles of the Major Therapeutic Class in Idiopathic Pulmonary Fibrosis 14
3.3.1 Overview 14
3.3.2 Immunosuppresants 14
3.3.3 Anti-inflammatory Drugs 15
3.3.4 Antifibrotics 16
3.4 Key Takeaway 18
4 Idiopathic Pulmonary Fibrosis Market: Pipeline Assessment 19
4.1 Overview 19
4.2 Strategic Pipeline Assessment 19
4.2.1 Technology Trends Analytic Framework 19
4.3 Idiopathic Pulmonary Fibrosis Therapeutics - Promising Drugs under Clinical Development 20
4.4 Molecule Profile for Promising Drugs for Idiopathic Pulmonary Fibrosis under Clinical Development 22
4.4.1 Letairis (ambrisentan) 22
4.4.2 Tracleer (bosentan) 23
4.4.3 Enbrel (etanercept) 24
4.4.4 Veldona (Oral interferon alfa) 25
4.5 Idiopathic Pulmonary Fibrosis Therapeutics Market - Clinical Pipeline by Mechanism of Action 26
4.6 Idiopathic Pulmonary Fibrosis Pipeline - Pipeline by Clinical Phases of Development 27
4.6.1 Idiopathic Pulmonary Fibrosis Therapeutics - Phase III Clinical Pipeline 28
4.6.2 Idiopathic Pulmonary Fibrosis Therapeutics - Phase II Clinical Pipeline 29
4.6.3 Idiopathic Pulmonary Fibrosis Therapeutics - Phase I Clinical Pipeline 29
4.6.4 Idiopathic Pulmonary Fibrosis Therapeutics - Preclinical Pipeline 30
4.7 Discontinued / Suspended Drug for Idiopathic Pulmonary Fibrosis 31
4.8 Key Takeaway 31
5 Idiopathic Pulmonary Fibrosis : Implications for Future Market Competition 32
6 Idiopathic Pulmonary Fibrosis Market: Future Players in the Idiopathic Pulmonary Fibrosis Market 34
6.1 Introduction 34
6.2 Gilead Sciences, Inc., California 34
6.2.1 Overview 34
6.2.2 Respiratory Disease Portfolio 36
6.2.3 Idiopathic Pulmonary Fibrosis Product Portfolio 36
6.3 Actelion Ltd. 37
6.3.1 Overview 37
6.3.2 Respiratory Disease Portfolio 38
6.3.3 Idiopathic Pulmonary Fibrosis Product Portfolio 38
6.4 Amgen Inc. 39
6.4.1 Overview 39
6.4.2 Respiratory Disease Portfolio 40
6.4.3 Idiopathic Pulmonary Fibrosis Product Portfolio 40
6.5 InterMune, Inc. 41
6.5.1 Overview 41
6.5.2 Respiratory Disease Portfolio 43
6.6 Amarillo Biosciences 44
6.6.1 Overview 44
6.6.2 Respiratory Disease Portfolio 45
6.6.3 Idiopathic Pulmonary Fibrosis Product Portfolio 46
7 Idiopathic Pulmonary Fibrosis Market: Appendix 47
7.1 Market Definitions 47
7.2 Abbreviations 47
7.3 Research Methodology 49
7.3.1 Coverage 49
7.3.2 Secondary Research 50
7.3.3 Forecasting 50
7.3.4 Primary Research 53
7.3.5 Expert Panel validation 53
7.4 Contact Us 53
7.5 Disclaimer 53
7.6 Sources 54

1.1 List of Tables
Table 1: Idiopathic Pulmonary Fibrosis Therapeutics, Global, Market Revenues ($m), 2001-2009 7
Table 2: Idiopathic Pulmonary Fibrosis Therapeutics, Global, Market Forecast ($m), 2009-2017 8
Table 3: Major Marketed Products Comparison in the Idiopathic Pulmonary Fibrosis Market, 2010 18
Table 4: Idiopathic Pulmonary Fibrosis Therapeutics - Most Promising Drugs Under Clinical Development, 2010 20
Table 5: Idiopathic Pulmonary Fibrosis Therapeutics - Phase III Clinical Pipeline, 2010 28
Table 6: Idiopathic Pulmonary Fibrosis Therapeutics - Phase II Clinical Pipeline, 2010 29
Table 7: Idiopathic Pulmonary Fibrosis Therapeutics - Phase I Clinical Pipeline, 2010 29
Table 8: Idiopathic Pulmonary Fibrosis Therapeutics - Preclinical Pipeline, 2010 30
Table 9: List of Discontinued Drugs for Idiopathic Pulmonary Fibrosis, 2010 31
Table 10: Gilead Sciences, Inc. -Respiratory Pipeline Products, 2010 36
Table 11: Actelion Ltd. -Respiratory Pipeline Products, 2010 38
Table 12: Amgen Inc. - Respiratory Disease Pipeline Products, 2010 40
Table 13: InterMune, Inc- Respiratory Disease Pipeline Products, 2010 43
Table 14: Amarillo Biosciences - Respiratory Disease Pipeline Products, 2010 45

1.2 List of Figures
Figure 1: Idiopathic Pulmonary Fibrosis Therapeutics, Global, Market Revenues ($m), 2001-2009 7
Figure 2: Idiopathic Pulmonary Fibrosis Therapeutics, Global, Market Forecast ($m), 2009-2017 8
Figure 3: Opportunity and Unmet Need in the Idiopathic Pulmonary Fibrosis Market, 2010 11
Figure 4: Strategic Competitor Assessment of the Major Marketed Products for Idiopathic Pulmonary Fibrosis, 2010 14
Figure 5: Technology Trends Analytic Framework of the Idiopathic Pulmonary Fibrosis Pipeline, 2010 19
Figure 6: Technology Trends Analytic Framework of the Idiopathic Pulmonary Fibrosis Pipeline - Description, 2010 20
Figure 7: Idiopathic Pulmonary Fibrosis Therapeutics - Clinical Pipeline by Mechanism of Action, 2010 27
Figure 8: Idiopathic Pulmonary Fibrosis Pipeline by Phase of Clinical Development, 2010 27
Figure 9: Implications for Future Market Competition in the Idiopathic Pulmonary Fibrosis Market, 2010 32
Figure 10: Idiopathic Pulmonary Fibrosis Therapeutics Market - Clinical Pipeline by Company, 2010 34
Figure 11: GlobalData Methodology, 2010 49
Figure 12: GlobalData Market Forecasting Model, 2010 52

Companies mentionedGilead Sciences, Inc
Actelion Ltd
Amgen Inc
InterMune, Inc
Amarillo Biosciences

 

http://www.live-pr.com/en/...monary-fibrosis-pipeline-r1048743538.htm

Antworten
Kleine_prinz:

Analysis of the current and future market

 
15.02.11 16:16
#000000; overflow: hidden; border-top: medium none; border-right: medium none; text-decoration: none">Global Data: Pipieline Assessment and Market Forecasts for Idiopathic Pulmonary
Edit Article | Posted: Feb 14, 2011 |Comments:



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GlobalData, the industry analysis specialist's new report, "Idiopathic Pulmonary Fibrosis - Pipeline Assessment and Market Forecasts to 2017" is an essential source of information and analysis on the global idiopathic pulmonary fibrosis market. The report identifies the key trends shaping and driving the global idiopathic pulmonary fibrosis market. The report also provides insight on the prevalent competitive landscape and the emerging players expected to bring significant shift in the market positioning of the existing market leaders. Most importantly, the report provides valuable insight on the pipeline products within the global idiopathic pulmonary fibrosis sector. This report is built using data and information sourced from proprietary databases, primary and secondary research and in house analysis by GlobalData's team of industry experts. The global Idiopathic Pulmonary Fibrosis (IPF) market was valued at $88m in 2009. It is expected to increase with a compound annual growth rate (CAGR) of 23% from $88m in 2009 to $462m by 2017. Earlier, the IPF market was underserved due to a lack of approved products. In October 2008, the Japanese manufacturer Shionogi received approval for Pirespa in Japan. It is under regulatory review for approval in the US and EU. The expected increase in sales is due to the expected approval of Pirespa in the US and the EU and also the expected launch of Tracleer and Letiaris. Growth in the IPF market is being driven by the sales of Pirespa, off-label drug use and the anticipated approval of Letiaris and Tracleer. Gilead's Letiaris and Actelion's Tracleer are the most anticipated molecules in the IPF market.

 

For Sample Pages please click the link below

 

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This report offers you:

 

* The report provides information on the key driver and challenges of the idiopathic pulmonary fibrosis market. Its scope includes:

* Annualized global idiopathic pulmonary fibrosis market revenues data from 2001 to 2009, forecast forward for eight years to 2017.

* Pipeline analysis data providing a split across the different phases, mechanisms of action being developed and emerging trends. Key classes of mechanism of action include enzyme inhibitors, protein inhibitors, endothelin A antagonists, combination therapy, TNF alpha antagonists, platelet aggregation inhibitors, interferon alpha, interleukin inhibitors, immunosuppresants, growth hormone inhibitors, gene therapy, LPA1 receptor antagonists, tumor growth factor inhibitors and NK-1 antagonists.

* Analysis of the current and future market competition in the global idiopathic pulmonary fibrosis market. Key market players covered are Gilead Sciences, Actelion Ltd., Amgen Inc., InterMune Inc. and Amarillo Biosciences.

* Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

* Key topics covered include strategic competitor assessment, market characterization, unmet needs and the implications for the future market associated with idiopathic pulmonary fibrosis therapeutics.

 

For More Information  please click the link below

 

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#52

Kleine_prinz:

Interessant... ;-))

 
23.03.11 17:22

PAUL TIBBITS Director Purchase Mar 21, 2011 6,321,832

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Kleine_prinz:

The effects of high dose interferon..

 
10.05.11 11:06

 

The effects of high dose interferon-beta1a on plasma microparticles: Correlation with MRI parameters

Journal of Neuroinflammation, 05/10/2011    

Lowery–Nordberg – This study’s data suggest that serial  measurement of plasma microparticles [PMP], particularly in the initial  stages of MS [when neuro–inflammatory cascades are more intense], may  serve as reliable and reproducible surrogate markers of response to  INF–beta1a therapy for MS. In addition, the progressive decline in  plasma levels of PMPCD31+ and PMPCD54+ further supports the concept that  IFN–beta1a exerts stabilizing effect on the cerebral endothelial cells  during pathogenesis of MS.

Methods
  • During the  prospective 1–year study, this study used flow cytometry to measure  changes in plasma microparticles [PMP] bearing CD31 [PMPCD31+], CD146  [PMPCD146+], and CD54/ICAM–1 [PMPCD54+] in 16 consecutive patients with  relapsing–remitting MS [RRMS] before and after 3, 6, and 12 months of  subcutaneous therapy with interferon–beta1a [44 micrograms, 3X weekly].
  • At each visit, clinical exams and expanded disability status scale [EDSS] scores were recorded.
 Results
  • Plasma levels of PMPCD31+, and PMPCD54+ were significantly reduced by treatment with IFN–beta1a.
  • PMPCD146+ appeared to decrease only at 3 months, this protection did not persist and was lost at 6 and 12 months.
  • In addition, the decrease in plasma levels of PMPCD31+ and PMPCD54+  levels were associated with a significant decrease in the number and  volume of contrast enhancing T1–weighted lesions.

www.mdlinx.com/neurology/xml-article.cfm/3597980

 

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Kleine_prinz:

Form 10-Q for AMARILLO BIOSCIENCES INC

 
19.05.11 16:32

Form 10-Q for AMARILLO BIOSCIENCES INC

19-May-2011

Quarterly Report

 


ITEM 2. Management's Discussion and Analysis of Financial Condition and Results of Operations

The following discussion should be read in conjunction with our financial statements and the notes thereto which appear elsewhere in this report. The results shown herein are not necessarily indicative of the results to be expected in any future periods. This discussion contains forward-looking statements based on current expectations, which involve uncertainties. Actual results and the timing of events could differ materially from the forward-looking statements as a result of a number of factors. Readers should also carefully review factors set forth in other reports or documents that we file from time to time with the Securities and Exchange Commission.

Company Goal - FDA Approval and Commercialization of Oral Interferon. Amarillo Biosciences, Inc. (OTCBB: AMAR), is the world leader in the development of low-dose interferon for oral delivery and is conducting Phase 2 clinical studies testing oral interferon in animal and human diseases. We have changed our focus from Orphan Diseases (small markets) to treatment of diseases with large markets to attract large pharma partners. Our funding strategy is to seek private placement and partner funding to complete Phase 2 clinical studies for influenza, chronic cough in COPD patients, and hepatitis C; then seek large pharma partners to fund and help with the regulatory approval process in the US and Europe. We believe that our technology and the large, billion-dollar markets for these disease indications will attract global pharma partners sometime later this year or early next year.

 


Intellectual Property
Our portfolio consists of patents with claims that encompass method of use or treatment with interferon and composition of matter and manufacturing. We currently own or license five patents related to low-dose orally delivered interferon, and one issued patent on our dietary supplement. We have completed more than 100 pre-clinical (animal) and human studies of the safety and efficacy of low-dose orally delivered interferon.

Technology - Non-toxic Interferon
Injectable interferon is FDA-approved to treat some neoplastic, viral and autoimmune diseases. Many patients experience moderate to severe side effects that result in discontinuance of injectable interferon therapy. Our main product is a natural human interferon alpha delivered into the oral cavity as a lozenge in low (nanogram) doses. The lozenge dissolves in the mouth where interferon binds to surface (mucosal) cells in the mouth and throat resulting in stimulation of immune mechanisms. Orally delivered interferon has been shown to activate hundreds of immune system genes in the peripheral blood. Human studies have shown that oral interferon is safe and effective against viral and autoimmune diseases. Oral interferon is given in concentrations 10,000 times less than that usually given by injection. The Company's low dose formulation results in almost no side effects; high dose injectable interferon causes adverse effects in at least 50% of recipients.

Governmental or FDA approval is required for our principal products. Our progress toward approval is discussed under each specific indication, below.

Influenza
Influenza, commonly referred to as the flu, is an infectious disease caused by RNA viruses of the family Orthomyxoviridae that affects birds and mammals. The most common symptoms of the disease are chills, fever, sore throat, muscle pains, severe headache, coughing, weakness/fatigue and general discomfort. Influenza spreads around the world in seasonal epidemics, resulting in the deaths of between 250,000 and 500,000 people every year, up to millions in some pandemic years. On average 41,400 people died each year in the United States between 1979 and 2001 from influenza. Two publications in the April 2009 issue of the Journal of Virology report that interferon placed in the nose of guinea pigs or ferrets significantly suppresses replication of influenza virus. These publications reinforce the Company's view that low-dose interferon is protective against influenza.

Further support of the efficacy of oral interferon against influenza was generated by The University of Western Australia in a Phase 2 clinical trial with 200 healthy volunteers during the 2009 winter cold/flu season in Australia. The study found that volunteers who took oral interferon had less severe cold/flu symptoms, compared to volunteers who received placebo. Publication of these results is pending.

In January 2011, CytoPharm, Inc., ABI's licensee for Taiwan and China, launched an influenza treatment study in Taiwan. Up to 60 patients being treated with Tamiflu for influenza A infection of less than 48 hours duration may be randomly assigned to co-treatment with oral IFN or placebo. The aim of the study is to examine whether the combination of oral IFN and Tamiflu is superior to Taimflu alone in the treatment of influenza illness.

 


Chronic Cough in COPD
COPD affects approximately 10% of the population over 40, is a growing problem, and is the 4th leading cause of death in the world. Chronic obstructive pulmonary disease (COPD) is a clinical condition with a progressive airflow limitation that is poorly reversible and characteristic of chronic bronchitis and emphysema. The causes of COPD include tobacco smoke, occupational dusts, chemicals, vapors and environmental pollutants. COPD is estimated to affect more that 600 million people worldwide. There are no effective therapies for emphysema, nor are there efficient clinical management strategies.

Data from a Phase 2 clinical study at Texas Tech University shows that treatment with oral interferon leads to a rapid and significant reduction in the cough associated with idiopathic pulmonary fibrosis (IPF), resulting in improved quality of life. Blinded, controlled studies in the US and Canada showed that oral interferon relieves chronic coughing in horses with COPD-like disease. A proof-of-concept study of low-dose oral interferon as treatment of chronic cough is ongoing at Texas Tech University. This clinical study is a Phase 2, randomized, double-blind, placebo-controlled, parallel trial in which 40 eligible volunteers with IPF- or COPD-associated chronic cough will be randomly assigned to one of two groups in equal numbers to receive either oral interferon or placebo lozenges. Treatment will be given three times daily for 4 weeks, and patients will be followed for 4 weeks post-treatment to assess durability of response. The study will evaluate the ability of oral interferon to reduce the frequency and severity of chronic cough, compared to placebo.

Hepatitis C
ABI's licensee CytoPharm, Inc. is funding an ongoing Phase 2 study of oral interferon treatment of hepatitis C virus-infected patients in Taiwan. The study is exploring the ability of oral interferon to reduce virologic relapse in patients who have completed standard therapy with pegylated interferon plus Ribavirin. Up to 50% of patients with certain genotypes of HCV relapse after receiving standard therapy, so reducing this relapse rate will represent a major breakthrough in the management of HCV. Completion of the study is expected by the end of 2011 with final results to be available in early 2012. Enrollment was completed in 2010 with 167 subjects.

Strategic Alliance with HBL
Hayashibara Biochemical Laboratories, Inc. ("HBL") was established in 1970 to engage in research and development. It is a subsidiary of Hayashibara Company, Ltd., a privately-owned Japanese holding corporation with diversified subsidiaries. For more than 130 years, the Hayashibara Company, Ltd. and its predecessors have been applying microbiological technology to the starch industry for the production of maltose and other sugars.

In 1981, HBL established the Fujisaki Institute to accelerate development of industrial methods for the production of biologics and to sponsor clinical trials for such products. In 1985, HBL built the Fujisaki Cell Center to support basic research. In 1987, HBL successfully accomplished the mass production of human cells in an animal host by producing human cells in hamsters. This made it possible to economically produce a natural form of human interferon alpha and other biologics. HBL also has developed and obtained patents for technology relating to the production of interferon alpha-containing lozenges by which the stability of the interferon alpha activity can be maintained for up to 24 months at room temperature and up to five years if the product is refrigerated. We believe that the use of such lozenges gives us advantages over competitive technologies in terms of cost, taste and ease of handling. On March 13, 1992, we entered into a Joint Development and Manufacturing/Supply Agreement with HBL (the "Development Agreement"). Such Development Agreement was subsequently amended on

 


January 17, 1996; May 10, 1996; and September 7, 2001. The current expiration date of the Development Agreement is March 12, 2014, at which time it will automatically renew for an additional three (3) years, unless the parties agree otherwise. Among other things, the Development Agreement provides us with a source of natural human interferon alpha for use in the Company's interferon alpha-containing products.

HBL is part of the Hayashibara Group of companies, which announced on February 2, 2011 on its website in Japan that it had filed a petition for corporate reorganization with the Tokyo District Court. In a letter to customers dated February 2, 2011, Mr. Hideki Matsushima, who has been appointed by the Tokyo District Court to be the provisional administrator of HBL, made the following statement, "We believe that we will be able to ensure a stable supply of our products, since we have been permitted by the Tokyo District Court to pay our debts to our suppliers related to the purchase of raw materials for our products, on the condition that our suppliers will continue to do business with us under the pre-existing payment terms and conditions." Based on this statement from Mr. Matsushima, ABI does not expect any disruption in the supply of interferon or ACM from HBL.

Strategic Alliance with Nobel.
A licensing and supply agreement was executed in September 2004 with a Turkish pharmaceutical company, NOBEL ILAC SANAYII VE TICARET A.S., providing the rights to oral low-dose interferon-alpha for the treatment of Behcet's disease in Turkey and in Azerbaijan, Bosnia & Herzegovina, Bulgaria, Croatia, Georgia, Kazakhstan, Kyrghyzstan, Macedonia, Romania, Russia, Saudi Arabia, Slovenia, Tajikistan, Turkmenistan, Uzbekistan, and Federal Republic of Yugoslavia.

Strategic Alliance with Bumimedic.
In January 2006, a license and distribution agreement was executed with Bumimedic (Malaysia) Sdn. Bhd, a Malaysian pharmaceutical company that is a part of the Antah HealthCare Group, to market our low-dose interferon (natural human IFN) in Malaysia. Bumimedic will seek registration for our natural human IFN and commence marketing the product after approval. The terms of the agreement call for Bumimedic to manufacture lozenges from bulk natural human IFN (supplied by Hayashibara Biochemical Laboratories); package the lozenges and distribute them to local hospitals, pharmacies and clinics in Malaysia. Pursuant to the agreement, the Company will receive a series of payments, in three stages: upon formal execution of the distribution agreement, upon regulatory approval, and upon production. The Company will also receive a royalty on the sale of the natural human IFN.

Strategic Alliance with CytoPharm.
In November 2006, the Company entered into a License and Supply Agreement with CytoPharm, Inc., a Taipei, Taiwan-based biopharmaceutical company whose parent company is Vita Genomics, Inc., the largest biotech company in Taiwan, specializing in pharmacogenomics and is a specialty Clinical Research Organization. Under the terms of the Agreement, CytoPharm and its subsidiary will conduct all clinical trials, and seek to obtain regulatory approvals in both China and Taiwan (the "Territory") to launch our low dose oral interferon in the Territory for influenza and hepatitis B ("HBV") and hepatitis C ("HCV") indications. According to the Agreement, CytoPharm will make payments to the Company upon reaching certain milestones and will also pay royalties on low dose oral interferon sales in the Territory.

In March 2008, the Company entered into a Supply Agreement for Animal Health with CytoPharm, Inc. Under the terms of the Agreement, CytoPharm will conduct all clinical trials, and seek to obtain regulatory regulatory approvals in China and Taiwan (the "Territory") to launch

 


our low dose oral interferon in the Territory for treatment of diseases and other healthcare applications of swine, cattle and poultry. CytoPharm will make payments to us upon reaching certain milestones and will also pay royalties on low dose oral interferon sales in the Territory.

Strategic Alliance with Intas Pharmaceuticals.
On January 7, 2010, the Company entered into a License and Supply Agreement with Intas Pharmaceuticals Ltd., an India-based pharmaceutical company with three decades of experience in the healthcare industry and a global presence in 42 countries worldwide. Under the terms of the agreement, Intas will pay the Company a royalty on net sales in India and Nepal after marketing approval is obtained.

Strategic Alliance with Cadila Healthcare On October 18, 2010, the Company entered into a License and Supply Agreement with Cadila Healthcare of Amedabad, India. The Company will supply anhydrous crystalline maltose (ACM) to Cadila for sale as an active ingredient in nutraceutical and healthcare products for human consumption to relieve dry mouth in India and Nepal.

Strategic Alliance with Oasis Diagnostics On January 12, 2011, the Company entered into a License and Supply Agreement with Oasis Diagnostics of Vancouver, WA. The Company will supply ACM to Oasis for sale as an active ingredient in nutraceutical and healthcare products for human consumption to relieve dry mouth in China, Taiwan and the Americas.

Equity Funding. In the first quarter of 2011, the Company sold 200 unregistered shares of preferred stock for $100 per share, convertible to common stock with a $0.10 conversion price. Net proceeds from the stock sale were $18,000 after payment of $2,000 in commissions.

Results of Operations for Quarters Ended March 31, 2011 and 2010:

Revenues. During the quarter ended March 31, 2011, $1,320 from dietary supplement sales was generated compared to $96 for the quarter ended March 31, 2010, an increase of $1,224 (1275%). During the quarter ended March 31, 2011, $1,400 of ACM sales was generated compared to no ACM sales for the quarter ended March 31, 2010, an increase of $1,400 (100%).

Research and Development Expenses. Research and development expenses of $86,945 were incurred for the quarter ended March 31, 2011, compared to $101,288 for the quarter ended March 31, 2010, a decrease of $14,343 (14%). The decrease was mostly because oral warts, influenza and hepatitis C costs and personnel costs were lower in the first quarter of 2011. The oral warts in HIV+ patients and influenza studies were mostly completed in 2009.

Selling, General and Administrative Expenses. Selling, general and administrative expenses of $111,224 were incurred for the first quarter in 2011, compared to $175,162 for the first quarter of 2010, a decrease of $63,938 (37%). Most of this decrease was due to lower salaries, Black-Scholes option expense, PR/IR, insurance and stock grants than in the first quarter of 2011.

 


Change in Fair Value of Derivative Instruments. Change in fair value of derivative instruments was realized as a $610 loss in the first quarter of 2011 compared to $63,733 gain in the first quarter of 2010. Derivative liabilities increased $610 from December 31, 2010 to March 31, 2011.

Other Income. During the three-month period ended March 31, 2011, $300 interest and other income was generated compared to no interest and other income for the three-month period ended March 31, 2010.

Net Operating Loss. In the three-month period ended March 31, 2011, the Company's net operating loss was $196,880 compared to a net operating loss for the three-month period ended March 31, 2010 of $276,411, a $79,531 (29%) reduction. The operating loss was lower mostly because the $63,938 (37%) reduction in Selling, General and Administrative expenses.

Net Loss. In the three-month period ended March 31, 2011, the Company's net loss was $220,253 compared to a net loss for the three-month period ended March 31, 2010 of $235,447 a $15,194 (6%) reduction. The operating loss was lower mostly because of the derivative liabilities decrease, due to a return of 12,000,000 warrants to the Company in December 2010.

Liquidity Needs: On March 31, 2011, the Company had available $1,539 cash and had a working capital deficit (current assets less current liabilities) of $3,685,197. Current liabilities include two $1 million notes, $773,486 of accrued interest and $78,360 of accrued expenses owed to Hayashibara Biochemical Laboratories, Inc. (HBL), and $220,000 of notes, and $426 of accrued interest owed to Paul Tibbits. Accrued payroll and vacation expenses owed mostly to officers is $385,021. Derivative liabilities from warrants with embedded variable features valued at $60,394 are also included in the working capital deficit. That leaves approximately $307,657 of accounts payables and accrued expenses in the working capital deficit.

Assuming there is no decrease in current accounts payable, and accounting for various one-time expenses, the Company's negative cash flow for operating activities plus patent filings, the Company's cash burn rate is approximately $66,000 per month. The Company's continued losses and lack of liquidity raise substantial doubt about whether the Company is able to continue as a going concern for a reasonable period of time. The Company's ability to continue as a going concern is dependent upon several factors including, but not limited to, the Company's ability to generate sufficient cash flows to meet its obligations on a timely basis, obtain license and milestone fees, obtain additional financing and continue to obtain supplies and services from its vendors. The Company will need to raise additional funds in order to fully execute its 2011 Plan. The Company is currently pursuing potential investors for funding. In addition, the Company is also pursuing potential pharmaceutical partners to provide upfront license fee payments and funding for clinical studies. There can be no assurance that private placement funding or pharmaceutical partner funding will become available.

Forward-Looking Statements: Certain statements made in this Plan of Operations and elsewhere in this report are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995 (the "Act"). Forward-looking statements include, without limitation, any statement that may predict, forecast, indicate or imply future results, performance, achievements, costs or expenses and may contain words such as "believe," "anticipate," "expect," "estimate," "project," "budget," or words or phrases of similar meaning. Forward-looking statements involve risks and uncertainties which may cause actual results to differ materially from those projected in the forward-looking statements.

 


Such risks and uncertainties are detailed from time to time in reports filed by the Company with the Securities and Exchange Commission, including Forms 8-K, 10-Q and 10-K and include among others the following: promulgation and implementation of regulations by the U.S. Food and Drug Administration ("FDA"); promulgation and implementation of regulations by foreign governmental instru&#65533;mentalities with functions similar to those of the FDA; costs of research and development and clinical trials, including without limitation, costs of clinical supplies, packaging and inserts, patient recruitment, trial monitoring, trial evaluation and publication; and possible difficulties in enrolling a sufficient number of qualified patients for certain clinical trials. The Company is also dependent upon a broad range of general economic and financial risks, such as possible increases in the costs of employing and/or retaining qualified personnel and consultants and possible inflation which might affect the Company's ability to remain within its budget forecasts. The principal uncertainties to which the Company is presently subject are its inability to ensure that the results of trials performed by the Company will be sufficiently favorable to ensure eventual regulatory approval for commercial sales, its inability to accurately budget at this time the possible costs associated with hiring and retaining of additional personnel, uncertainties regarding the terms and timing of one or more commercial partner agreements and its ability to continue as a going concern.

The risks cited here are not exhaustive. Other sections of this report may include additional factors which could adversely impact the Company's business and future prospects. Moreover, the Company is engaged in a very competitive and rapidly changing industry.

New risk factors emerge from time to time and it is not possible for management to predict all such risk factors, nor can it assess the impact of all such risk factors on the Company's business, or the extent to which any factor or combination of factors may cause actual results to differ materially from those projected in any forward-looking statements. Given these risks and uncertainties, investors should not place undue reliance on forward-looking statements as a prediction of actual future events.

 


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Kleine_prinz:

News ;-))

 
19.07.11 22:16

Amarillo Biosciences Teams With Bio-Stasis International to Launch Dietary Supplement Virapress

Press Release Source: Amarillo Biosciences, Inc. On Tuesday July 19, 2011, 11:14 am EDT

AMARILLO, TX--(Marketwire - 07/19/11) - Amarillo Biosciences, Inc. (ABI) (OTC.BB:AMAR - News) today announced that it has formed an alliance with Bio-Stasis International, Inc., a dietary supplement internet marketer, to launch Bio-Stasis International's Virapress. Bio-Stasis plans to embark on an extensive internet marketing program for Virapress on August 1, 2011, targeting alternative and complimentary medical practitioners.

Virapress is a dietary supplement derived from a bovine protein extract produced by ABI and will be marketed with claims to improve health and enhance immunity. In parallel with Bio-Stasis International's internet marketing campaign, ABI will market its bovine extract to health food stores and internationally under ABI's brand name. ABI has already received serious inquiries about distribution rights from marketers in 9 different countries in the Middle East and Africa and has commenced negotiations on international distribution rights.

"We expect our internet marketing campaign to significantly increase the market for Virapress and, also, its primary ingredient, bovine extract," said Lawrence H. Griffin, president, Bio-Stasis International.

Virapress has not been evaluated by the Food and Drug Administration, and should not take the place of a regular medical evaluation by a licensed health practitioner.

About Bio-Stasis International, Inc.

Bio-Stasis is committed to the promotion of natural products which have been shown to promote health and healing. Each Bio-Stasis product must have scientific evidence to support effectiveness, without side effects. For additional information, please visit the Bio-Stasis International Inc.'s website www.virapress.com

About Amarillo Biosciences
Amarillo Biosciences, Inc. is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 6% of Amarillo Biosciences shares and has provided over $18 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R&D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including influenza, hepatitis C, chronic cough, and opportunistic infections in patients who are HIV positive. The Company has invested nearly $40 million to establish oral interferon as a therapeutic agent. The majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the web at http://www.amarbio.com/.

Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" and "Item 7A. Qualitative and Quantitative Disclosures About Market Risk" of the Company's Form 10-K for the fiscal year ended December 31, 2010.

Contact:



Investor Relations:
Philippe Niemetz
PAN Consultants, Ltd.
e-mail: p.niemetz@panconsultants.com
Tel: 800-477-7570; 212-344-6464
Fax: 212-618-1276
Investor Inquiries:
Josh Tyrell
Interactive Business Alliance, LLC
e-mail: jtyrell@ibaconsultingllc.com
Tel: 866-525-4714
 

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