Press Release: Q1 2026: double-digit sales and business EPS growth

Paris, April 23, 2026

Q1 sales growth of 13.6% at CER¹ and business earnings per share (EPS)² of €1.88

• Pharma launches sales increased by 49.6%, reaching €1.2 billion, driven primarily by Ayvakit, ALTUVIIIO, and Sarclisa
• Dupixent sales increased by 30.8% to €4.2 billion, a strong start to 2026
• Vaccines sales increased by 2.1% to €1.3 billion, benefiting from Heplisav-B
• Research and Development expenses reached €1.7 billion, up by 1.5%
• Selling and general expenses reached €2.3 billion, up by 11.6%, mainly due to the effect of recent acquisitions
• Business EPS was €1.88, up by 14.0% at CER; 5.0% at actual exchange rates; IFRS EPS €1.34 

Pipeline progress

• Five regulatory approvals, all in immunology
• Positive pipeline readouts: venglustat in the rare disease GD3 (phase 3) and lunsekimig in respiratory diseases (phase 2)
• Two regulatory submission acceptances, one phase 3 study start, four regulatory designations (breakthrough, orphan)

Capital allocation

• Completion of the Dynavax acquisition
• Completion of €921 million of the €1 billion share buyback programme

Other major developments

• 25-year partnership with WHO³ in sleeping sickness: positive CHMP recommendation paves the way in Africa for acoziborole, the first single-dose oral treatment co-developed with DNDi⁴

Guidance affirmed

• In 2026, sales are expected to grow by a high single-digit percentage at CER. Business EPS at CER is expected to grow slightly faster than sales (before share buyback), delivering profitable growth.⁵ 

Olivier Charmeil, interim Chief Executive Officer: “We had a strong start to 2026 with double-digit sales and business EPS growth. Sales increased by 13.6%, supported by Pharma launches and recent acquisitions. Dupixent sales were above the €4 billion quarterly mark again and grew by 30.8%. Business EPS was up by 14.0%, reflecting a measured growth of 7.0% in total operating expenses. We obtained five regulatory approvals, all in immunology, achieved one positive phase 3 study readout for venglustat in rare diseases, and reported encouraging phase 2 data for lunsekimig in respiratory diseases. We reiterate our guidance for 2026: we continue to expect sales to grow by a high single-digit percentage and business EPS to grow slightly faster than sales, at constant exchange rates, delivering profitable growth. We are also looking forward to welcoming Belén Garijo as the new CEO of Sanofi from next month.”