MDxHealth Licensee Exact Sciences Confirms Use of Biomarker and Methylation Technology in its Advanced Colon Cancer Test

Montag, 10.01.2011 08:05 von Hugin - Aufrufe: 145

DURHAM, NC, and LIEGE, BELGIUM - January 10, 2011 - MDxHealth SA (NYSE Euronext:
MDXH), a leading molecular diagnostics company in the field of personalized
cancer treatment, today announced that Exact Sciences (Nasdaq: EXAS) has
confirmed that it is using an MDxHealth methylation biomarker together with
MDxHealth's methylation specific PCR (MSP) platform in Cologuard(TM), a non-
invasive stool-based DNA colon cancer screening test. This confirmation has
triggered a milestone payment to MDxHealth from Exact Sciences. MDxHealth will
also receive royalties on net sales once the test is commercialized. Under the
terms of a licensing agreement announced in August 2010, Exact Sciences has been
evaluating several MDxHealth methylation biomarkers, among other markers, as
well as the MSP technology in studies with its stool-based colon cancer test.
 
In October 2010, Exact Sciences presented positive data from a study involving
samples from 1,100 patients demonstrating the ability of Cologuard to detect 64
percent of colorectal pre-cancers and 85 percent of colorectal cancers. Exact
Sciences is now preparing to enroll several thousand patients in a prospective
trial to obtain approval from the U.S. Food and Drug Administration. Trial
completion is expected in 2012 and the test, if approved, could be launched soon
after.
 
"Following the promising Cologuard data presented in October, confirmation that
our biomarker and MSP technology have been incorporated is a significant event
for MDxHealth as it further validates our core capabilities," said Dr. Jan
Groen, Chief Executive Officer of MDxHealth. "Exact Sciences has a unique focus
on colon cancer and is well positioned to ensure patients will benefit from this
important colon cancer screening test in the near term."
 
About MDxHealth
 
MDxHealth is a leading molecular diagnostics company that develops and
commercializes oncology-based molecular diagnostic testing for personalized
medicine. The company's tests are based on proprietary gene methylation
technology and assist physicians with the diagnosis of cancer, prognosis of
recurrence risk, and prediction of response to a specific therapy. MDxHealth
collaborates with leading cancer research centers such as Johns Hopkins
University, Duke University, Lovelace Respiratory Research Institute, Eastern
Virginia Medical School, Cleveland Clinic, Memorial Sloan Kettering, and major
European academic medical centers. The company has a number of commercial and
collaborative partnerships with LabCorp, Merck & Co./Schering Plough,
GlaxoSmithKline Biologicals, Roche, Merck Serono, Qiagen, and other industry
leaders.
 
MDxHealth to present today at Biotech Showcase in San Francisco
 
MDxHealth will present at the Biotech Showcase Conference in San Francisco, on
Monday, Jan. 10, 2011. Dr. Jan Groen, chief executive officer, will make a
formal presentation on the company at 2 p.m. Pacific time. The Biotech Showcase
runs parallel to the 28th Annual J.P. Morgan Healthcare Conference, and takes
place at Parc 55 Wyndham San Francisco - Union Square.
 
MDxHealth is now on Twitter
 
Key topics and information linked to MDxHealth activities will be uploaded on
Twitter and available for reading to the MDxHealth followers. Tweets will be
generated on a regular basis.
 
In order to keep you updated on events and activities in the field of interest
of MDxHealth, we kindly invite you to be a follower of MDxHealth on Twitter. To
do so please follow the instructions below:
 
Go to www.twitter.com
 
Sign up and create your account.
 
You will get an e-mail where you have to confirm to have full access to twitter.
 
Go to www.twitter.com/mdxhealth and push the bottom " + Follow"
 
Now you should be a Follower of MDxHealth. Please join us in this new
experience.
 
For more information:
 
Dr. Jan Groen, CEO                           Hans Herklots
 
MDxHealth                                        Capricorn One
 
+32 4 364 20 70                                 +41 79 598 7149
 
This press release contains forward-looking statements and estimates with
respect to the anticipated future performance of MDxHealth and the market in
which it operates. Such statements and estimates are based on assumptions and
assessments of known and unknown risks, uncertainties and other factors, which
were deemed reasonable but may not prove to be correct. Actual events are
difficult to predict, may depend upon factors that are beyond the Company's
control, and may turn out to be materially different. MDxHealth expressly
disclaims any obligation to update any such forward-looking statements in this
release to reflect any change in its expectations with regard thereto or any
change in events, conditions or circumstances on which any such statement is
based unless required by law or regulation
 
2011-01-10 Exact Sciences ENG:
http://hugin.info/137314/R/1478172/414074.pdf
 
This announcement is distributed by Thomson Reuters on behalf of
Thomson Reuters clients. The owner of this announcement warrants that:
(i) the releases contained herein are protected by copyright and
other applicable laws; and
(ii) they are solely responsible for the content, accuracy and
originality of the information contained therein.

Source: MdxHealth via Thomson Reuters ONE
 
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