PR Newswire
SYDNEY, April 25, 2016
SYDNEY, April 25, 2016 /PRNewswire/ -- Benitec Biopharma Limited (ASX: BLT; NASDAQ: BNTC; NASDAQ: BNTCW), a biotechnology company developing innovative therapeutics based on its patented gene-silencing technology called ddRNAi or 'expressed RNAi', today announced acceptance of five presentations at the 19th Annual Meeting of American Society of Gene and Cell Therapy (ASGCT) being held in Washington D.C. on May 4-7, 2016. The abstracts cover the scientific results from three of Benitec's programs: hepatitis B, OPMD and hepatitis C, with the key findings briefly summarised below.
David Suhy, Chief Scientific Officer of Benitec Biopharma, stated: "This meeting is one of the most important international meetings on gene and cell therapy. To have five abstracts accepted demonstrates the interest and importance in the work that Benitec is doing across its programs and will give our research further exposure to a global audience. As we move ahead with our programs, we will update both the scientific and investor communities on our clinical priorities and next phases of development."
1. Oral Presentation: BB-HB-331, a DNA-Directed RNA Interference (ddRNAi) Agent Targeting Hepatitis B Virus (HBV), Can Effectively Suppress HBV In Vitro and In Vivo
Presenter: David Suhy, PhD
In a press release dated March 8, 2016, Benitec reported the data from the full 56-day in vivo study which demonstrated a further marked improvement over the results above. Dr Suhy will present the full data set at the conference.
2. Oral Presentation: Gene Therapy Rescues Disease Phenotype in the Oculopharyngeal Muscular Dystrophy Mouse Model
Presenter: David Suhy, PhD (on behalf of Professor George Dickson)
3. Oral Presentation: Phase I/IIa Study of TT-034, a DNA-Directed RNA Interference (ddRNAi) Agent Delivered as a Single Administration for the Treatment of Subjects with Chronic Hepatitis C Virus (HCV)
Presenter: David Suhy, PhD
4. Poster: Durable Expression of TT-034 in Cynomolgus Monkey Hepatic and Cardiac Tissues without Long-Term Adverse Effects on Endogenous MicroRNA Levels
Presenter: David Suhy, PhD
5. Poster: A Comparison of scAAV8-TT-034 Mediated Transduction and shRNA Expression in Human Liver Biopsy Samples versus a Chimeric Mouse Model with Humanized Liver
Presenter: David Suhy, PhD
The full abstracts have been published on the conference website and can be accessed at the following link: http://www.abstractsonline.com/pp8/#!/4077. A copy of the oral presentations and posters will be accessible on May 4, 2016 by visiting the Investor sections of www.benitec.com and selecting News/Resources and Presentations.
For further information regarding Benitec and its activities, please contact the persons below, or visit the Benitec website at www.benitec.com
Company | Investor relations | United States |
| | |
Carl Stubbings | Buchan Consulting | PCG Advisory Group |
Chief Business Officer | Kyahn Williamson | Adam Holdsworth |
Tel: +61 (2) 9555 6986 | Head of Investor Communications | Managing Director of Investor Relations |
Email: cstubbings@benitec.com | Tel: +61 (3) 9866 4722 | Tel: + 1 646-862-4607 |
| Email: kwilliamson@buchanwe.com.au | Email: adamh@pcgadvisory.com |
| | |
| | Sean Leous |
| | Managing Director of Public Relations |
| | Tel: +1 646-863-8998 |
| | Email: sleous@pcgadvisory.com |
About Benitec Biopharma Limited:
Benitec Biopharma Limited (ASX: BLT; NASDAQ: BNTC; NASDAQ: BNTCW) is a biotechnology company developing innovative therapeutics based on its patented gene-silencing technology called ddRNAi or 'expressed RNAi'. Based in Sydney, Australia with labs in Hayward, CA (USA) and collaborators and licensees around the world, the company is developing ddRNAi-based therapeutics for chronic and life-threatening human conditions including hepatitis B, wet age-related macular degeneration and OPMD. Benitec has also licensed ddRNAi to other biopharmaceutical companies for applications including HIV/AIDS, Huntington's Disease, chronic neuropathic pain and retinitis pigmentosa.
Safe Harbor Statement:
This press release contains "forward-looking statements" within the meaning of section 27A of the US Securities Act of 1933 and section 21E of the US Securities Exchange Act of 1934. Any forward-looking statements that may be in the press release are subject to risks and uncertainties relating to the difficulties in Benitec's plans to develop and commercialize its product candidates, the timing of the initiation and completion of preclinical and clinical trials, the timing of patient enrolment and dosing in clinical trials, the timing of expected regulatory filings, the clinical utility and potential attributes and benefits of ddRNAi and Benitec's product candidates, potential future out-licenses and collaborations, the intellectual property position and the ability to procure additional sources of financing. Accordingly, you should not rely on those forward-looking statements as a prediction of actual future results.
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SOURCE Benitec Biopharma Limited
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